Simultaneous determination of residual antiparasitic lactones in bovine muscle and liver by liquid chromatography with fluorescence detection
Abamectin, doramectin, eprinomectin, ivermectin, milbemectin, and moxidectin in bovine muscle and liver were extracted with acetonitrile. The extracts were partitioned with n-hexane and then evaporated to dryness. The residue was cleaned up on Bond Elute NH2 cartridge, and the drugs were eluted from the cartridge with methanol-ethyl acetate (3 + 7). The eluate was evaporated to dryness, and residues were derivatized with N,N-dimethylformamide-acetic anhyride-1-methylimidazole. The derivatives were determined by liquid chromatography with fluorescence detection. Recoveries of the 6 drugs were 79.6-63.8% in muscle and 71.6-60.6% in liver at 0.01 ppm levels. The quantitation limits were 5 ppb for each drug.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2003 |
|---|---|
| Erschienen: |
2003 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:86 |
|---|---|
| Enthalten in: |
Journal of AOAC International - 86(2003), 3 vom: 24. Mai, Seite 490-3 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Nagata, Tomoko [VerfasserIn] |
|---|
| Themen: |
5U8924T11H |
|---|
| Anmerkungen: |
Date Completed 26.09.2003 Date Revised 10.12.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
|
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| PPN (Katalog-ID): |
NLM126128642 |
|---|
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|---|---|---|---|
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| 041 | |a eng | ||
| 100 | 1 | |a Nagata, Tomoko |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Simultaneous determination of residual antiparasitic lactones in bovine muscle and liver by liquid chromatography with fluorescence detection |
| 264 | 1 | |c 2003 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 26.09.2003 | ||
| 500 | |a Date Revised 10.12.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Abamectin, doramectin, eprinomectin, ivermectin, milbemectin, and moxidectin in bovine muscle and liver were extracted with acetonitrile. The extracts were partitioned with n-hexane and then evaporated to dryness. The residue was cleaned up on Bond Elute NH2 cartridge, and the drugs were eluted from the cartridge with methanol-ethyl acetate (3 + 7). The eluate was evaporated to dryness, and residues were derivatized with N,N-dimethylformamide-acetic anhyride-1-methylimidazole. The derivatives were determined by liquid chromatography with fluorescence detection. Recoveries of the 6 drugs were 79.6-63.8% in muscle and 71.6-60.6% in liver at 0.01 ppm levels. The quantitation limits were 5 ppb for each drug | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Anti-Bacterial Agents |2 NLM | |
| 650 | 7 | |a Antiparasitic Agents |2 NLM | |
| 650 | 7 | |a Lactones |2 NLM | |
| 650 | 7 | |a Macrolides |2 NLM | |
| 650 | 7 | |a abamectin |2 NLM | |
| 650 | 7 | |a 5U8924T11H |2 NLM | |
| 650 | 7 | |a Ivermectin |2 NLM | |
| 650 | 7 | |a 70288-86-7 |2 NLM | |
| 650 | 7 | |a eprinomectin |2 NLM | |
| 650 | 7 | |a 75KP30FD8O |2 NLM | |
| 650 | 7 | |a doramectin |2 NLM | |
| 650 | 7 | |a KGD7A54H5P |2 NLM | |
| 650 | 7 | |a moxidectin |2 NLM | |
| 650 | 7 | |a NGU5H31YO9 |2 NLM | |
| 700 | 1 | |a Miyamoto, Fumio |e verfasserin |4 aut | |
| 700 | 1 | |a Hasegawa, Yasuyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Ashizawa, Eiichi |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of AOAC International |d 1993 |g 86(2003), 3 vom: 24. Mai, Seite 490-3 |w (DE-627)NLM074913743 |x 1944-7922 |7 nnns |
| 773 | 1 | 8 | |g volume:86 |g year:2003 |g number:3 |g day:24 |g month:05 |g pages:490-3 |
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| 952 | |d 86 |j 2003 |e 3 |b 24 |c 05 |h 490-3 | ||