Superantigens and vasculitis
Superantigens are microbial products, that may activate in a polyclonal way, a high number of T lymphocytes bearing a specific VB segment of TCR; the best characterized are staphylococcal and streptogenic toxins. In a review of the literature, we summarize the role of these superantigens in primitive vasculitis, specially in Kawasaki syndrome and Wegener's granulomatosis. This pathogenic model highlights the complex relations between infection and autoimmunity.
Medienart: |
Artikel |
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Erscheinungsjahr: |
2003 |
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Erschienen: |
2003 |
Enthalten in: |
Zur Gesamtaufnahme - volume:154 |
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Enthalten in: |
Annales de medecine interne - 154(2003), 2 vom: 13. März, Seite 96-100 |
Sprache: |
Französisch |
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Weiterer Titel: |
Superantigènes et vascularites primitives |
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Beteiligte Personen: |
Hamidou, Mohamed [VerfasserIn] |
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Themen: |
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Anmerkungen: |
Date Completed 31.07.2003 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM125148097 |
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100 | 1 | |a Hamidou, Mohamed |e verfasserin |4 aut | |
245 | 1 | 0 | |a Superantigens and vasculitis |
246 | 3 | 3 | |a Superantigènes et vascularites primitives |
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500 | |a Date Completed 31.07.2003 | ||
500 | |a Date Revised 15.11.2006 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Superantigens are microbial products, that may activate in a polyclonal way, a high number of T lymphocytes bearing a specific VB segment of TCR; the best characterized are staphylococcal and streptogenic toxins. In a review of the literature, we summarize the role of these superantigens in primitive vasculitis, specially in Kawasaki syndrome and Wegener's granulomatosis. This pathogenic model highlights the complex relations between infection and autoimmunity | ||
650 | 4 | |a English Abstract | |
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650 | 4 | |a Review | |
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