Assessment of microcirculation disturbance with nuclear cardiology in a patient with coronary ectasia : a case report

A 69-year-old woman presented with dyspnea on exertion. Echocardiography showed dilatation and diffuse hypokinesis of the left ventricle. 99mTc-tetrofosmin myocardial SPECT showed moderately reduced uptake in the anteroseptal wall and the inferior wall on the rest images, but was improved on the ATP loading images. 123I-BMIPP myocardial SPECT showed severely reduced uptake in the anterior wall and the inferior wall. These SPECT findings suggested ischemic heart disease rather than dilated cardiomyopathy. Coronary angiography showed no organic stenosis, but diffuse coronary ectasia was noted in three vessels. Intravascular ultrasound revealed remarkable coronary ectasia, with a maximal diameter of 8.2 mm. Coronary flow velocity as measured by Doppler blood flow guide wire was remarkably reduced. Coronary spasms were not provocated by ergonovine loading test. These findings suggested that microvascular thrombi and disturbance of dilatation caused myocardial ischemia in this patient. We treated the patient with ticlopidine and nicorandil. Following treatment left ventricle wall motion, 99mTc-tetrofosmin and 123I-BMIPP myocardial SPECT findings were improved.

Medienart:

Artikel

Erscheinungsjahr:

2003

Erschienen:

2003

Enthalten in:

Zur Gesamtaufnahme - volume:40

Enthalten in:

Kaku igaku. The Japanese journal of nuclear medicine - 40(2003), 1 vom: 30. Feb., Seite 17-22

Sprache:

Japanisch

Beteiligte Personen:

Nishikawa, Susumu [VerfasserIn]
Ito, Kazuki [VerfasserIn]
Takata, Hiroki [VerfasserIn]
Tsubakimoto, Yoshinori [VerfasserIn]
Yuba, Tatsuya [VerfasserIn]
Adachi, Yoshihiko [VerfasserIn]
Kato, Shuji [VerfasserIn]
Azuma, Akihiro [VerfasserIn]
Sugihara, Hiroki [VerfasserIn]
Nakagawa, Masao [VerfasserIn]

Themen:

0J7USQ749M
42FOP1YX93
Case Reports
Fatty Acids
Iodine Radioisotopes
Iodobenzenes
Iodofiltic acid
Journal Article
Organophosphorus Compounds
Organotechnetium Compounds
Radiopharmaceuticals
Technetium tc-99m tetrofosmin

Anmerkungen:

Date Completed 02.06.2003

Date Revised 20.02.2017

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM124724485