Use of percutaneous radial artery catheter for peripheral blood progenitor cell collection in pediatric patients

BACKGROUND: Leukapheresis procedures require adequate flow rates, which in children may frequently involve invasive vascular access placement.

STUDY DESIGN AND METHODS: A minimally invasive peripheral radial artery catheter was used for drawing blood in 85 leukapheresis procedures performed in 33 pediatric patients. Blood return to the patients was provided by either a central Broviac-type catheter or a peripheral venous access. The patients' age range was 1 to 18 years (median, 9.5) and the weight range was 9 to 73 kg (median, 29 kg). Vasocan Braunüle Luer Lock IV cannulas (22 gauge in 78 and 20 gauge in 7) were placed percutaneously under local anesthesia, and in 8 patients, catheter placement was carried out during general anesthesia for other procedures. A continuous flow cell separator was used in all cases (Fresenius AS104 in 23 and AS204 in 62).

RESULTS: Flow rates ranged from 18 to 45 mL per minute, the mean number of total blood volumes processed was 2.07 (range, 0.51-2.51), and the mean duration of the procedures was 150 minutes (range, 90-260). The 22-gauge cannulas provided adequate flow rates independently of patient age and weight. No significant thrombotic, embolic, hemorrhagic, ischemic, or infectious complications were observed.

CONCLUSION: Peripheral radial artery catheters are safe, are minimally invasive, and provide steady, high-flow rates, and they should be considered for patients requiring leukapheresis and lacking a suitable vascular access for drawing blood.

Medienart:

Artikel

Erscheinungsjahr:

2003

Erschienen:

2003

Enthalten in:

Zur Gesamtaufnahme - volume:43

Enthalten in:

Transfusion - 43(2003), 2 vom: 15. Feb., Seite 254-8

Sprache:

Englisch

Beteiligte Personen:

Bambi, Franco [VerfasserIn]
Fontanazza, Silvia [VerfasserIn]
Messeri, Andrea [VerfasserIn]
Lippi, Alma [VerfasserIn]
Tucci, Fabio [VerfasserIn]
Tamburini, Angela [VerfasserIn]
Tintori, Veronica [VerfasserIn]
Casini, Tommaso [VerfasserIn]
Lacitignola, Laura [VerfasserIn]
Tondo, Annalisa [VerfasserIn]
Veltroni, Marinella [VerfasserIn]
Bernini, Gabriella [VerfasserIn]
Faulkner, Lawrence B [VerfasserIn]

Themen:

Evaluation Study
Journal Article

Anmerkungen:

Date Completed 24.04.2003

Date Revised 10.12.2019

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM123377374