Immediate anesthesia recovery and psychomotor function of patient after prolonged anesthesia with desflurane, sevoflurane or isoflurane

OBJECTIVE: To compare the anesthetic maintenance and early postoperative recovery and psychomotor function in patients who have been anesthestized with desflurane, sevoflurane or isoflurane during prolonged open urological surgery.

PATIENTS AND METHODS: Seventy-five patients were randomly assigned to receive desflurane, sevoflurane or isoflurane with N2O 60% for anesthetic maintenance. The concentration of each drug was adjusted to maintain arterial pressure and heart rate +/- 20% of baseline. After the operation the anesthetics were discontinued and times until eye opening, spontaneous breathing, extubation and orientation were recorded. In the post-anesthesia recovery ward we applied the Newman-Trieger and Aldrete tests and recorded instances of nausea and vomiting and need for analgesia during the first 24 hours after surgery.

RESULTS: The groups were similar with regard to demographic features, anesthetic maintenance, duration of anesthesia and relative doses of the anesthetics used. Recovery times in the operating room were significantly shorter (p < 0.05) after anesthesia with desflurane and sevoflurane than with isoflurane, with no significant differences between the desflurane and sevoflurane groups (duration of anesthesia 198 +/- 90, 171 +/- 67 and 191 +/- 79; eye opening 7.6 +/- 3.7, 7.8 +/- 3.0 and 11.9 +/- 4.5; time until extubation 7.8 +/- 3.0, 8.3 +/- 3.0 and 11.0 +/- 3.5 for desflurane, sevoflurane and isoflurane, respectively; all data in minutes). Recovery in the post-anesthetic recovery ward was similar for all three groups.

CONCLUSIONS: Anesthetic maintenance was comparable with all three drugs. Desflurane and sevoflurane demonstrated advantages over isoflurane during recovery from anesthesia in the operating theater. No significant differences were found in psychomotor recovery, nausea and/or vomiting or requirements for postoperative analgesia.

Medienart:

Artikel

Erscheinungsjahr:

2000

Erschienen:

2000

Enthalten in:

Zur Gesamtaufnahme - volume:47

Enthalten in:

Revista espanola de anestesiologia y reanimacion - 47(2000), 9 vom: 08. Nov., Seite 386-92

Sprache:

Spanisch

Weiterer Titel:

Recuperación anestésica inmediata y función psicomotriz de los pacientes tras anestesia prolongada con desflurano, sevoflurano o isoflurano

Beteiligte Personen:

Pensado Castiñeiras, A [VerfasserIn]
Rama Maceiras, P [VerfasserIn]
Molins Gauna, N [VerfasserIn]
Fiqueira Moure, A [VerfasserIn]
Vásquez Fidalgo, A [VerfasserIn]

Themen:

38LVP0K73A
Analgesics
Anesthetics, Inhalation
CRS35BZ94Q
CYS9AKD70P
Clinical Trial
Comparative Study
Desflurane
Isoflurane
Journal Article
Methyl Ethers
Randomized Controlled Trial
Sevoflurane

Anmerkungen:

Date Completed 31.05.2001

Date Revised 30.11.2018

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM112139108