Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause
Triptans, 5-HT1B/1D agonists used in migraine treatment, are rarely involved in serious coronary events due to vasospasm. 5 HT1 receptors mediate vasodilation and vasoconstriction of coronary arteries. Reports of serious coronary events mainly concern patients with known risk factors for coronary artery disease. It is prudent to obtain a thorough medical history before treatment with a triptan is started. If chest pain occurs, the possibility of coronary ischemia should be investigated. Stroke, a known complication to migraine, has also been reported in patients treated with triptans, but available data do not suggest that triptans, when correctly used, greatly increase the risk.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2000 |
|---|---|
| Erschienen: |
2000 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:97 |
|---|---|
| Enthalten in: |
Lakartidningen - 97(2000), 25 vom: 21. Juni, Seite 3078-84 |
| Sprache: |
Schwedisch |
|---|
| Weiterer Titel: |
Hjärt-kärlbiverkningar av triptaner vid migrän finns men är sällsynta. 5-HT-receptormedierad extrakraniell vasokonstriktion oftast orsak |
|---|
| Beteiligte Personen: |
Hedenmalm, K [VerfasserIn] |
|---|
| Themen: |
8R78F6L9VO |
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| Anmerkungen: |
Date Completed 25.09.2000 Date Revised 16.11.2017 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM108353028 |
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| 245 | 1 | 0 | |a Cardiovascular side-effects of triptanes in migraine exist but are rare. 5-HT receptor mediated extracranial vasoconstriction is the most common cause |
| 246 | 3 | 3 | |a Hjärt-kärlbiverkningar av triptaner vid migrän finns men är sällsynta. 5-HT-receptormedierad extrakraniell vasokonstriktion oftast orsak |
| 264 | 1 | |c 2000 | |
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| 500 | |a Date Completed 25.09.2000 | ||
| 500 | |a Date Revised 16.11.2017 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Triptans, 5-HT1B/1D agonists used in migraine treatment, are rarely involved in serious coronary events due to vasospasm. 5 HT1 receptors mediate vasodilation and vasoconstriction of coronary arteries. Reports of serious coronary events mainly concern patients with known risk factors for coronary artery disease. It is prudent to obtain a thorough medical history before treatment with a triptan is started. If chest pain occurs, the possibility of coronary ischemia should be investigated. Stroke, a known complication to migraine, has also been reported in patients treated with triptans, but available data do not suggest that triptans, when correctly used, greatly increase the risk | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
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| 650 | 7 | |a Vasoconstrictor Agents |2 NLM | |
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