Time trends in biological fertility in Britain
BACKGROUND: There is evidence of a decline in semen quality in some countries, including Britain, in recent decades. This retrospective cohort study examined the hypothesis that biological fertility had also declined. The trend in couple fertility was assessed by means of time to pregnancy (TTP--a sensitive and validated measure of fertility.
METHODS: A representative sample of the British population aged 16-59 years was surveyed. TTP was obtained for all births conceived after unprotected intercourse that began during 1961-93, excluding contraceptive failures. The sample size was 1540.
FINDINGS: In contrast to the original hypothesis, this study found that fertility has increased; the rising trend was accompanied by slight dips during 1976-80 and 1986-90. These results were consistent between male and female respondents, and undiminished by adjustment for possible confounding factors. A stronger and more consistent relation was found with the year when unprotected intercourse started (a period effect) than with the year of birth of either partner (a birth cohort effect).
INTERPRETATION: The findings could not be explained by trends in age at first birth, increased treatment of subfertility, or changes in oral contraceptive use. If a decline in male fertility has occurred, it has been more than compensated for by a countervailing increase in couple fertility.
| Errataetall: |
CommentIn: Lancet. 2000 Jun 3;355(9219):1928-9. - PMID 10859034 |
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| Medienart: |
Artikel |
| Erscheinungsjahr: |
2000 |
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| Erschienen: |
2000 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:355 |
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| Enthalten in: |
Lancet (London, England) - 355(2000), 9219 vom: 03. Juni, Seite 1961-5 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Joffe, M [VerfasserIn] |
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| Anmerkungen: |
Date Completed 03.07.2000 Date Revised 24.11.2016 published: Print CommentIn: Lancet. 2000 Jun 3;355(9219):1928-9. - PMID 10859034 Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM107837900 |
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| 245 | 1 | 0 | |a Time trends in biological fertility in Britain |
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| 500 | |a Date Completed 03.07.2000 | ||
| 500 | |a Date Revised 24.11.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a CommentIn: Lancet. 2000 Jun 3;355(9219):1928-9. - PMID 10859034 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: There is evidence of a decline in semen quality in some countries, including Britain, in recent decades. This retrospective cohort study examined the hypothesis that biological fertility had also declined. The trend in couple fertility was assessed by means of time to pregnancy (TTP--a sensitive and validated measure of fertility | ||
| 520 | |a METHODS: A representative sample of the British population aged 16-59 years was surveyed. TTP was obtained for all births conceived after unprotected intercourse that began during 1961-93, excluding contraceptive failures. The sample size was 1540 | ||
| 520 | |a FINDINGS: In contrast to the original hypothesis, this study found that fertility has increased; the rising trend was accompanied by slight dips during 1976-80 and 1986-90. These results were consistent between male and female respondents, and undiminished by adjustment for possible confounding factors. A stronger and more consistent relation was found with the year when unprotected intercourse started (a period effect) than with the year of birth of either partner (a birth cohort effect) | ||
| 520 | |a INTERPRETATION: The findings could not be explained by trends in age at first birth, increased treatment of subfertility, or changes in oral contraceptive use. If a decline in male fertility has occurred, it has been more than compensated for by a countervailing increase in couple fertility | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Biology | |
| 650 | 4 | |a Cohort Analysis | |
| 650 | 4 | |a Demographic Factors | |
| 650 | 4 | |a Developed Countries | |
| 650 | 4 | |a Europe | |
| 650 | 4 | |a Fertility | |
| 650 | 4 | |a Fertility Measurements | |
| 650 | 4 | |a Genitalia | |
| 650 | 4 | |a Genitalia, Male | |
| 650 | 4 | |a Northern Europe | |
| 650 | 4 | |a Physiology | |
| 650 | 4 | |a Population | |
| 650 | 4 | |a Population Dynamics | |
| 650 | 4 | |a Pregnancy Rate | |
| 650 | 4 | |a Reproduction | |
| 650 | 4 | |a Research Methodology | |
| 650 | 4 | |a Research Report | |
| 650 | 4 | |a Retrospective Studies | |
| 650 | 4 | |a Semen | |
| 650 | 4 | |a Seminal Vesicles | |
| 650 | 4 | |a Studies | |
| 650 | 4 | |a Time Factors | |
| 650 | 4 | |a United Kingdom | |
| 650 | 4 | |a Urogenital System | |
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