Resuscitation of newborn infants with room air or oxygen
In this article we present results from the Resair 2 study in which we tested whether room air is more efficient than 100% oxygen in newborn resuscitation. Eleven participating centres in Egypt, Estonia, India, Norway, Philippines, and Spain recruited 609 infants who needed resuscitation at birth; of these, 288 were resuscitated with room air and 321 with 100% oxygen. There were no differences between the two groups with regard to outcome. One minute Apgar scores were significantly lower in the oxygen group than in the room air group. Median time to first breath was significantly delayed with 24 seconds in the oxygen group compared with the room air group. It seems that 100% oxygen depresses ventilation in newborn infants. Room air is as safe and efficient as 100% oxygen at least in most cases of newborn resuscitation. Further studies confirming these results are needed before new resuscitation routines are implemented.
Errataetall: |
CommentIn: Tidsskr Nor Laegeforen. 2000 Apr 10;120(10):1239. - PMID 10863358 |
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Medienart: |
Artikel |
Erscheinungsjahr: |
2000 |
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Erschienen: |
2000 |
Enthalten in: |
Zur Gesamtaufnahme - volume:120 |
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Enthalten in: |
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke - 120(2000), 1 vom: 10. Jan., Seite 25-8 |
Sprache: |
Norwegisch |
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Weiterer Titel: |
Gjenoppliving av nyfødte med romluft eller oksygen |
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Beteiligte Personen: |
Saugstad, O D [VerfasserIn] |
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Themen: |
Clinical Trial |
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Anmerkungen: |
Date Completed 25.05.2000 Date Revised 16.07.2008 published: Print CommentIn: Tidsskr Nor Laegeforen. 2000 Apr 10;120(10):1239. - PMID 10863358 Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM107409828 |
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520 | |a In this article we present results from the Resair 2 study in which we tested whether room air is more efficient than 100% oxygen in newborn resuscitation. Eleven participating centres in Egypt, Estonia, India, Norway, Philippines, and Spain recruited 609 infants who needed resuscitation at birth; of these, 288 were resuscitated with room air and 321 with 100% oxygen. There were no differences between the two groups with regard to outcome. One minute Apgar scores were significantly lower in the oxygen group than in the room air group. Median time to first breath was significantly delayed with 24 seconds in the oxygen group compared with the room air group. It seems that 100% oxygen depresses ventilation in newborn infants. Room air is as safe and efficient as 100% oxygen at least in most cases of newborn resuscitation. Further studies confirming these results are needed before new resuscitation routines are implemented | ||
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