A male contraceptive injection can be available within 5 years
After more than two decades of attempts to develop a safe male contraceptive, the goal now seems attainable. Spermatogenesis, which is dependent on endogenous testosterone production in the testes, may be controlled by such exogenous steroid hormones as testosterone, gestagens, or combinations of them. The recent development of gonadotrophin-releasing hormone (GnRH) antagonists has provided an added means of depressing testosterone production. Other targets for interference with male fertility are the germinal epithelium (e.g. using the cottonseed oil product, Gossypol, or Triptyrigeum Wilfordii extract), or the maturing sperm in the epididymis (using immunoactive substances).
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
1999 |
|---|---|
| Erschienen: |
1999 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:96 |
|---|---|
| Enthalten in: |
Lakartidningen - 96(1999), 38 vom: 22. Sept., Seite 4039-44 |
| Sprache: |
Schwedisch |
|---|
| Weiterer Titel: |
P-spruta för män kan vara i bruk inom fem år |
|---|
| Beteiligte Personen: |
Gottlieb, C [VerfasserIn] |
|---|
| Themen: |
33515-09-2 |
|---|
| Anmerkungen: |
Date Completed 28.10.1999 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
NLM104570997 |
|---|
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| 245 | 1 | 2 | |a A male contraceptive injection can be available within 5 years |
| 246 | 3 | 3 | |a P-spruta för män kan vara i bruk inom fem år |
| 264 | 1 | |c 1999 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
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| 500 | |a Date Completed 28.10.1999 | ||
| 500 | |a Date Revised 15.11.2006 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a After more than two decades of attempts to develop a safe male contraceptive, the goal now seems attainable. Spermatogenesis, which is dependent on endogenous testosterone production in the testes, may be controlled by such exogenous steroid hormones as testosterone, gestagens, or combinations of them. The recent development of gonadotrophin-releasing hormone (GnRH) antagonists has provided an added means of depressing testosterone production. Other targets for interference with male fertility are the germinal epithelium (e.g. using the cottonseed oil product, Gossypol, or Triptyrigeum Wilfordii extract), or the maturing sperm in the epididymis (using immunoactive substances) | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Androgens |2 NLM | |
| 650 | 7 | |a Contraceptive Agents, Male |2 NLM | |
| 650 | 7 | |a Drug Combinations |2 NLM | |
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| 650 | 7 | |a Gonadotropin-Releasing Hormone |2 NLM | |
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