Significance of free radicals in the pathogenesis of rheumatic diseases and possibilities of decreasing their pathogenic effects

The authors present the result of their work where they provide evidence that in inflammatory and degenerative diseases the break-down on superoxide in inadequate. This oxygen radicals and its metabolites play a significant role in the pathogenesis of these diseases. The authors revealed a severe defect in superoxide degeneration in particular in articular exudates of patients with active synovitis. Administration of the preparation Selzink-Plus of PRO.MED.CS Co. Prague which contains selenium, zinc, beta-cyrotene, vitamin C and E along with antirheumatic treatment improves according to the authors the breakdown of superoxide and its metabolites and improves thus the patient's prognosis. Long-term administration of the preparation seems to produce even better results.

Medienart:

Artikel

Erscheinungsjahr:

1998

Erschienen:

1998

Enthalten in:

Zur Gesamtaufnahme - volume:44

Enthalten in:

Vnitrni lekarstvi - 44(1998), 12 vom: 18. Dez., Seite 702-6

Sprache:

Tschechisch

Weiterer Titel:

Význam volných radikálů v patogenezi revmatických chorob a moznosti snízení jejich patogenního působení

Beteiligte Personen:

Kucera, M [VerfasserIn]
Racek, J [VerfasserIn]
Holecek, V [VerfasserIn]
Trefil, L [VerfasserIn]

Themen:

11062-77-4
Drug Combinations
English Abstract
Free Radicals
H6241UJ22B
J41CSQ7QDS
Journal Article
Research Support, Non-U.S. Gov't
Selenium
Superoxides
Vitamins
Zinc

Anmerkungen:

Date Completed 30.08.1999

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM103541659