Forearm bone density in users of Depo-Provera as a contraceptive method
OBJECTIVE: To determine the influence of depot medroxyprogesterone acetate (MPA) on bone mineral density when used as a contraceptive method.
DESIGN: Cross-sectional study.
SETTING: Academic tertiary-care hospital.
PATIENT(S): Fifty premenopausal women who had used depot MPA as a contraceptive method for > or =1 year and 50 women who had never used hormonal contraceptive methods.
INTERVENTION(S): Bone mineral density was evaluated at the midshaft and at the distal radius of the nondominant forearm using single x-ray absorptiometry.
MAIN OUTCOME MEASURE(S): Bone mineral density.
RESULT(S): Bone mineral density at the midshaft of the forearm was lower in depot MPA users than in women who had never used hormonal contraceptive methods, but the difference was not statistically significant. At the distal portion, bone mineral density was significantly lower in the study group. The duration of depot MPA use was not related to bone mineral density.
CONCLUSION(S): Women > or =35 years of age presented with a lower bone mineral density only at the distal portion of the forearm after the use of depot MPA for > or =1 year. However, this decrease was not related to the duration of depot MPA use. It is not possible to conclude that women who use depot MPA are at risk of osteoporosis.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1999 |
|---|---|
| Erschienen: |
1999 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:71 |
|---|---|
| Enthalten in: |
Fertility and sterility - 71(1999), 5 vom: 26. Mai, Seite 849-52 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Bahamondes, L [VerfasserIn] |
|---|
| Anmerkungen: |
Date Completed 12.05.1999 Date Revised 07.07.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM101636032 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM101636032 | ||
| 003 | DE-627 | ||
| 005 | 20231222122700.0 | ||
| 007 | tu | ||
| 008 | 231222s1999 xx ||||| 00| ||eng c | ||
| 028 | 5 | 2 | |a pubmed24n0339.xml |
| 035 | |a (DE-627)NLM101636032 | ||
| 035 | |a (NLM)10231044 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Bahamondes, L |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Forearm bone density in users of Depo-Provera as a contraceptive method |
| 264 | 1 | |c 1999 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 12.05.1999 | ||
| 500 | |a Date Revised 07.07.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: To determine the influence of depot medroxyprogesterone acetate (MPA) on bone mineral density when used as a contraceptive method | ||
| 520 | |a DESIGN: Cross-sectional study | ||
| 520 | |a SETTING: Academic tertiary-care hospital | ||
| 520 | |a PATIENT(S): Fifty premenopausal women who had used depot MPA as a contraceptive method for > or =1 year and 50 women who had never used hormonal contraceptive methods | ||
| 520 | |a INTERVENTION(S): Bone mineral density was evaluated at the midshaft and at the distal radius of the nondominant forearm using single x-ray absorptiometry | ||
| 520 | |a MAIN OUTCOME MEASURE(S): Bone mineral density | ||
| 520 | |a RESULT(S): Bone mineral density at the midshaft of the forearm was lower in depot MPA users than in women who had never used hormonal contraceptive methods, but the difference was not statistically significant. At the distal portion, bone mineral density was significantly lower in the study group. The duration of depot MPA use was not related to bone mineral density | ||
| 520 | |a CONCLUSION(S): Women > or =35 years of age presented with a lower bone mineral density only at the distal portion of the forearm after the use of depot MPA for > or =1 year. However, this decrease was not related to the duration of depot MPA use. It is not possible to conclude that women who use depot MPA are at risk of osteoporosis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Americas | |
| 650 | 4 | |a Biology | |
| 650 | 4 | |a Brazil | |
| 650 | 4 | |a Comparative Studies | |
| 650 | 4 | |a Contraception | |
| 650 | 4 | |a Contraceptive Agents, Female--side effects | |
| 650 | 4 | |a Contraceptive Agents, Progestin--side effects | |
| 650 | 4 | |a Contraceptive Agents--side effects | |
| 650 | 4 | |a Demographic Factors | |
| 650 | 4 | |a Depo-provera--side effects | |
| 650 | 4 | |a Developing Countries | |
| 650 | 4 | |a Family Planning | |
| 650 | 4 | |a Fertility | |
| 650 | 4 | |a Fertility Measurements | |
| 650 | 4 | |a Latin America | |
| 650 | 4 | |a Longterm Effects--women | |
| 650 | 4 | |a Medroxyprogesterone Acetate--side effects | |
| 650 | 4 | |a Osteoporosis--women | |
| 650 | 4 | |a Parity | |
| 650 | 4 | |a Physiology | |
| 650 | 4 | |a Population | |
| 650 | 4 | |a Population Dynamics | |
| 650 | 4 | |a Research Methodology | |
| 650 | 4 | |a Research Report | |
| 650 | 4 | |a Risk Factors--women | |
| 650 | 4 | |a Skeletal Effects | |
| 650 | 4 | |a South America | |
| 650 | 4 | |a Studies | |
| 650 | 4 | |a Time Factors | |
| 650 | 4 | |a Women | |
| 650 | 7 | |a Contraceptive Agents, Female |2 NLM | |
| 650 | 7 | |a Medroxyprogesterone Acetate |2 NLM | |
| 650 | 7 | |a C2QI4IOI2G |2 NLM | |
| 700 | 1 | |a Perrotti, M |e verfasserin |4 aut | |
| 700 | 1 | |a Castro, S |e verfasserin |4 aut | |
| 700 | 1 | |a Faúndes, D |e verfasserin |4 aut | |
| 700 | 1 | |a Petta, C |e verfasserin |4 aut | |
| 700 | 1 | |a Bedone, A |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Fertility and sterility |d 1950 |g 71(1999), 5 vom: 26. Mai, Seite 849-52 |w (DE-627)NLM000040614 |x 1556-5653 |7 nnns |
| 773 | 1 | 8 | |g volume:71 |g year:1999 |g number:5 |g day:26 |g month:05 |g pages:849-52 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 71 |j 1999 |e 5 |b 26 |c 05 |h 849-52 | ||