Body weight and mortality : a prospective evaluation in a cohort of middle-aged men in Shanghai, China
BACKGROUND: The relationship between relative body weight and mortality has been well studied in Western populations and remains controversial. Little is known about the weight-mortality association in less well fed people in developing countries.
METHODS: A cohort of 18,244 Chinese men aged 45-64 years in Shanghai, China enrolled in a prospective study of diet and cancer during January 1986 through September 1989. At recruitment, height and usual body weight were collected through interview. An active, annual follow-up of the cohort was conducted for cancer and death. Proportional hazards regression method was used to examine the relation between body mass index (BMI, weight in kg/height in m2) and overall and cause-specific mortality.
RESULTS: By 28 February 1995, 1198 deaths (498 from cancer, 422 from cardio- and cerebrovascular disease, and 278 from other causes) had been identified. We found a U-shaped relation between BMI and total mortality among lifelong non-smokers. Compared with non-smokers with BMI 21.0-<23.5, the relative risk (RR) for all cause mortality was 1.73 (95% confidence interval [CI]: 1.23-2.42) for men with BMI <18.5 and 1.48 (95% CI: 1.07-2.03) for men with BMI > or =26 after adjustment for age, level of education, and alcohol drinking. The elevated risk of death in men with BMI > or =26 was largely due to fatal cardio- and cerebro-vascular diseases. There was a nearly twofold excess risk of death from cardio- and cerebrovascular diseases among lifelong non-smokers with BMI > or =26 compared with non-smokers with BMI 21-<23.5 (95% CI: 1.17-3.22). On the other hand, the increased overall mortality risk in men with BMI <18.5 was primarily due to causes of an infectious origin. Exclusion of the first 4 years of follow-up data did not materially alter the BMI-mortality associations.
CONCLUSION: Underweight and overweight both are associated with an increased risk of death in middle-aged Chinese men who never smoked cigarettes. The increased total mortality in overweight men is largely due to cardio- and cerebro-vascular diseases while the elevated risk of death in underweight men is attributed primarily to causes of an infectious nature.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1998 |
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| Erschienen: |
1998 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
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| Enthalten in: |
International journal of epidemiology - 27(1998), 5 vom: 09. Okt., Seite 824-32 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yuan, J M [VerfasserIn] |
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| Anmerkungen: |
Date Completed 04.02.1999 Date Revised 12.05.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM097765791 |
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| 041 | |a eng | ||
| 100 | 1 | |a Yuan, J M |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Body weight and mortality |b a prospective evaluation in a cohort of middle-aged men in Shanghai, China |
| 264 | 1 | |c 1998 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 04.02.1999 | ||
| 500 | |a Date Revised 12.05.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: The relationship between relative body weight and mortality has been well studied in Western populations and remains controversial. Little is known about the weight-mortality association in less well fed people in developing countries | ||
| 520 | |a METHODS: A cohort of 18,244 Chinese men aged 45-64 years in Shanghai, China enrolled in a prospective study of diet and cancer during January 1986 through September 1989. At recruitment, height and usual body weight were collected through interview. An active, annual follow-up of the cohort was conducted for cancer and death. Proportional hazards regression method was used to examine the relation between body mass index (BMI, weight in kg/height in m2) and overall and cause-specific mortality | ||
| 520 | |a RESULTS: By 28 February 1995, 1198 deaths (498 from cancer, 422 from cardio- and cerebrovascular disease, and 278 from other causes) had been identified. We found a U-shaped relation between BMI and total mortality among lifelong non-smokers. Compared with non-smokers with BMI 21.0-<23.5, the relative risk (RR) for all cause mortality was 1.73 (95% confidence interval [CI]: 1.23-2.42) for men with BMI <18.5 and 1.48 (95% CI: 1.07-2.03) for men with BMI > or =26 after adjustment for age, level of education, and alcohol drinking. The elevated risk of death in men with BMI > or =26 was largely due to fatal cardio- and cerebro-vascular diseases. There was a nearly twofold excess risk of death from cardio- and cerebrovascular diseases among lifelong non-smokers with BMI > or =26 compared with non-smokers with BMI 21-<23.5 (95% CI: 1.17-3.22). On the other hand, the increased overall mortality risk in men with BMI <18.5 was primarily due to causes of an infectious origin. Exclusion of the first 4 years of follow-up data did not materially alter the BMI-mortality associations | ||
| 520 | |a CONCLUSION: Underweight and overweight both are associated with an increased risk of death in middle-aged Chinese men who never smoked cigarettes. The increased total mortality in overweight men is largely due to cardio- and cerebro-vascular diseases while the elevated risk of death in underweight men is attributed primarily to causes of an infectious nature | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, U.S. Gov't, P.H.S. | |
| 650 | 4 | |a Asia | |
| 650 | 4 | |a Biology | |
| 650 | 4 | |a Body Weight | |
| 650 | 4 | |a Cardiovascular Effects | |
| 650 | 4 | |a Causes Of Death | |
| 650 | 4 | |a Cerebrovascular Effects | |
| 650 | 4 | |a China | |
| 650 | 4 | |a Demographic Factors | |
| 650 | 4 | |a Developing Countries | |
| 650 | 4 | |a Differential Mortality | |
| 650 | 4 | |a Diseases | |
| 650 | 4 | |a Eastern Asia | |
| 650 | 4 | |a Infections | |
| 650 | 4 | |a Mortality | |
| 650 | 4 | |a Physiology | |
| 650 | 4 | |a Population | |
| 650 | 4 | |a Population Dynamics | |
| 650 | 4 | |a Prospective Studies | |
| 650 | 4 | |a Research Methodology | |
| 650 | 4 | |a Risk Factors | |
| 650 | 4 | |a Studies | |
| 700 | 1 | |a Ross, R K |e verfasserin |4 aut | |
| 700 | 1 | |a Gao, Y T |e verfasserin |4 aut | |
| 700 | 1 | |a Yu, M C |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of epidemiology |d 1975 |g 27(1998), 5 vom: 09. Okt., Seite 824-32 |w (DE-627)NLM00011930X |x 1464-3685 |7 nnns |
| 773 | 1 | 8 | |g volume:27 |g year:1998 |g number:5 |g day:09 |g month:10 |g pages:824-32 |
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