Molecular epidemiology and trends of HIV-1 subtypes in Taiwan
To understand the trends of distribution and risk factors associated with different HIV-1 subtypes in different populations in Taiwan, blood samples and questionnaires were collected from 267 male and 21 female HIV-1-infected people in a multicenter survey from 1993 to 1996. This group represented about one quarter of the total registered HIV-1 cases in Taiwan. The HIV-1 subtypes were determined using V3-based peptide-enzyme immunoassays complemented by heteroduplex mobility assay and phylogenetic tree analysis. The results showed that in Taiwan, men were primarily infected with HIV-1B (68.2%) and HIV-1E (27.3%), whereas women were mainly infected with non-B subtypes (4.8% A, 4.8% C, 71.4% E, and 9.5% G). In addition, 71.4% of men with HIV-1B were homosexual or bisexual, whereas 56.2% of men with HIV-1E were heterosexual (p < .001). Although HIV-1E subtype came to Taiwan later than HIV-1B, it has become a major subtype in the heterosexual population.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1998 |
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| Erschienen: |
1998 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
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| Enthalten in: |
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 19(1998), 4 vom: 01. Dez., Seite 393-402 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chen, Y M [VerfasserIn] |
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| Anmerkungen: |
Date Completed 15.12.1998 Date Revised 24.10.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM097714712 |
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| 041 | |a eng | ||
| 100 | 1 | |a Chen, Y M |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Molecular epidemiology and trends of HIV-1 subtypes in Taiwan |
| 264 | 1 | |c 1998 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 15.12.1998 | ||
| 500 | |a Date Revised 24.10.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a To understand the trends of distribution and risk factors associated with different HIV-1 subtypes in different populations in Taiwan, blood samples and questionnaires were collected from 267 male and 21 female HIV-1-infected people in a multicenter survey from 1993 to 1996. This group represented about one quarter of the total registered HIV-1 cases in Taiwan. The HIV-1 subtypes were determined using V3-based peptide-enzyme immunoassays complemented by heteroduplex mobility assay and phylogenetic tree analysis. The results showed that in Taiwan, men were primarily infected with HIV-1B (68.2%) and HIV-1E (27.3%), whereas women were mainly infected with non-B subtypes (4.8% A, 4.8% C, 71.4% E, and 9.5% G). In addition, 71.4% of men with HIV-1B were homosexual or bisexual, whereas 56.2% of men with HIV-1E were heterosexual (p < .001). Although HIV-1E subtype came to Taiwan later than HIV-1B, it has become a major subtype in the heterosexual population | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Acquired Immunodeficiency Syndrome | |
| 650 | 4 | |a Asia | |
| 650 | 4 | |a Behavior | |
| 650 | 4 | |a Biology | |
| 650 | 4 | |a China | |
| 650 | 4 | |a Clinical Research | |
| 650 | 4 | |a Developing Countries | |
| 650 | 4 | |a Diseases | |
| 650 | 4 | |a Eastern Asia | |
| 650 | 4 | |a Epidemiology | |
| 650 | 4 | |a Genetics | |
| 650 | 4 | |a Health | |
| 650 | 4 | |a Heterosexuals | |
| 650 | 4 | |a Hiv Infections | |
| 650 | 4 | |a Homosexuals | |
| 650 | 4 | |a Public Health | |
| 650 | 4 | |a Research Methodology | |
| 650 | 4 | |a Research Report | |
| 650 | 4 | |a Risk Factors | |
| 650 | 4 | |a Sex Behavior | |
| 650 | 4 | |a Taiwan | |
| 650 | 4 | |a Viral Diseases | |
| 650 | 7 | |a HIV Antibodies |2 NLM | |
| 650 | 7 | |a HIV Envelope Protein gp120 |2 NLM | |
| 650 | 7 | |a Peptide Fragments |2 NLM | |
| 700 | 1 | |a Lee, C M |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, R Y |e verfasserin |4 aut | |
| 700 | 1 | |a Chang, H J |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association |d 1995 |g 19(1998), 4 vom: 01. Dez., Seite 393-402 |w (DE-627)NLM074698362 |x 1077-9450 |7 nnns |
| 773 | 1 | 8 | |g volume:19 |g year:1998 |g number:4 |g day:01 |g month:12 |g pages:393-402 |
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| 952 | |d 19 |j 1998 |e 4 |b 01 |c 12 |h 393-402 | ||