Cardiac sarcoidosis mimicking hypertrophic cardiomyopathy : clinical utility of radionuclide imaging for differential diagnosis
A 62-year-old woman with skin sarcoidosis was admitted to our hospital to ascertain whether she had cardiac involvement. Although she displayed no cardiac signs or symptoms, the electrocardiogram showed first-degree atrioventricular block, right bundle branch block with left anterior fascicular block, and giant negative T waves in the V3 lead. Echocardiography revealed marked hypertrophy localized in the basal portion of the interventricular septum (IVS) without systolic dysfunction, mimicking hypertrophic cardiomyopathy (HCM). Exercise thallium-201 myocardial imaging revealed redistribution in the anteroseptal region. Both gallium-67 (67Ga) and technetium-99m pyrophosphate (99mTc-PYP) scintigraphy revealed abnormal uptake in the myocardium. These findings disappeared after 2 months of steroid treatment. Reports of cardiac sarcoidosis mimicking HCM are rare. However, hypertrophy in the basal portion of the IVS is an important sign of early cardiac involvement in sarcoidosis. 67Ga and 99mTc-PYP scintigraphy were useful and necessary to differentiate this type of cardiac sarcoidosis from HCM.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1998 |
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| Erschienen: |
1998 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:62 |
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| Enthalten in: |
Japanese circulation journal - 62(1998), 6 vom: 12. Juni, Seite 465-8 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yazaki, Y [VerfasserIn] |
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| Themen: |
5L76I61H2B |
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| Anmerkungen: |
Date Completed 09.10.1998 Date Revised 17.08.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM095922261 |
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| 100 | 1 | |a Yazaki, Y |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Cardiac sarcoidosis mimicking hypertrophic cardiomyopathy |b clinical utility of radionuclide imaging for differential diagnosis |
| 264 | 1 | |c 1998 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 09.10.1998 | ||
| 500 | |a Date Revised 17.08.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a A 62-year-old woman with skin sarcoidosis was admitted to our hospital to ascertain whether she had cardiac involvement. Although she displayed no cardiac signs or symptoms, the electrocardiogram showed first-degree atrioventricular block, right bundle branch block with left anterior fascicular block, and giant negative T waves in the V3 lead. Echocardiography revealed marked hypertrophy localized in the basal portion of the interventricular septum (IVS) without systolic dysfunction, mimicking hypertrophic cardiomyopathy (HCM). Exercise thallium-201 myocardial imaging revealed redistribution in the anteroseptal region. Both gallium-67 (67Ga) and technetium-99m pyrophosphate (99mTc-PYP) scintigraphy revealed abnormal uptake in the myocardium. These findings disappeared after 2 months of steroid treatment. Reports of cardiac sarcoidosis mimicking HCM are rare. However, hypertrophy in the basal portion of the IVS is an important sign of early cardiac involvement in sarcoidosis. 67Ga and 99mTc-PYP scintigraphy were useful and necessary to differentiate this type of cardiac sarcoidosis from HCM | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Gallium Radioisotopes |2 NLM | |
| 650 | 7 | |a Thallium Radioisotopes |2 NLM | |
| 650 | 7 | |a Technetium Tc 99m Pyrophosphate |2 NLM | |
| 650 | 7 | |a 5L76I61H2B |2 NLM | |
| 700 | 1 | |a Isobe, M |e verfasserin |4 aut | |
| 700 | 1 | |a Hayasaka, M |e verfasserin |4 aut | |
| 700 | 1 | |a Tanaka, M |e verfasserin |4 aut | |
| 700 | 1 | |a Fujii, T |e verfasserin |4 aut | |
| 700 | 1 | |a Sekiguchi, M |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Japanese circulation journal |d 1961 |g 62(1998), 6 vom: 12. Juni, Seite 465-8 |w (DE-627)NLM000062375 |x 0047-1828 |7 nnns |
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