Prevalence of hypercoagulation conditions in patients with thrombosis in Northern Navarra
BACKGROUND: To determine the prevalence of hypercoagulability states in patients with thromboembolic disease in Septentrional Navarra.
PATIENTS AND METHODS: 74 patients were studied (13 female, mean age [+/- SD] 43.5 +/- 13.9 years, range 22-81) with: deep venous thrombosis (DVT) with or without pulmonary embolism (PE) in 15 patients; ischemic stroke (IS) in 20 patients and; myocardial infarction (MI) in 39 patients. Antithrombin III, C protein (CP), plasminogen, plasminogen activator inhibitor (PAI), total S protein (TSP), free S protein (FSP), lupus anticoagulant (LA) and anticardiolipin antibodies (ACA) type IgG were determined in all patients.
RESULTS: The prevalence of hypercoagulability state was 27% in patients with thromboembolic disease; 26.6% in patients with PE (20% with ACA and 6.6% with CP deficiency); 30% in patients with IS (15% with ACA, CP deficiency in 5%, FSP deficiency in 5%, and PAI raising in 10%) and in the 25.6% of patients with MI (15.3% with ACA, 2.5% with CP deficiency, 2.5% with TSP and FSP deficiency and PAI raising in the 7.6%).
CONCLUSIONS: In Septentrional Navarra population with thromboembolic disease the presence of hypercoagulable states is high. In our study, the most common hypercoagulable state was the presence of ACA, followed by PAI raising and by the CP deficiency.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1997 |
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| Erschienen: |
1997 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
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| Enthalten in: |
Anales de medicina interna (Madrid, Spain : 1984) - 14(1997), 9 vom: 06. Sept., Seite 450-4 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Prevalencia de los estados de hipercoagulabilidad en pacientes con trombosis en Navarra Septentrional |
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| Beteiligte Personen: |
Benedicto Aguirre, E [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 03.02.1998 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM093967896 |
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| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
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| 100 | 1 | |a Benedicto Aguirre, E |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Prevalence of hypercoagulation conditions in patients with thrombosis in Northern Navarra |
| 246 | 3 | 3 | |a Prevalencia de los estados de hipercoagulabilidad en pacientes con trombosis en Navarra Septentrional |
| 264 | 1 | |c 1997 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 03.02.1998 | ||
| 500 | |a Date Revised 15.11.2006 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: To determine the prevalence of hypercoagulability states in patients with thromboembolic disease in Septentrional Navarra | ||
| 520 | |a PATIENTS AND METHODS: 74 patients were studied (13 female, mean age [+/- SD] 43.5 +/- 13.9 years, range 22-81) with: deep venous thrombosis (DVT) with or without pulmonary embolism (PE) in 15 patients; ischemic stroke (IS) in 20 patients and; myocardial infarction (MI) in 39 patients. Antithrombin III, C protein (CP), plasminogen, plasminogen activator inhibitor (PAI), total S protein (TSP), free S protein (FSP), lupus anticoagulant (LA) and anticardiolipin antibodies (ACA) type IgG were determined in all patients | ||
| 520 | |a RESULTS: The prevalence of hypercoagulability state was 27% in patients with thromboembolic disease; 26.6% in patients with PE (20% with ACA and 6.6% with CP deficiency); 30% in patients with IS (15% with ACA, CP deficiency in 5%, FSP deficiency in 5%, and PAI raising in 10%) and in the 25.6% of patients with MI (15.3% with ACA, 2.5% with CP deficiency, 2.5% with TSP and FSP deficiency and PAI raising in the 7.6%) | ||
| 520 | |a CONCLUSIONS: In Septentrional Navarra population with thromboembolic disease the presence of hypercoagulable states is high. In our study, the most common hypercoagulable state was the presence of ACA, followed by PAI raising and by the CP deficiency | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Antibodies, Antiphospholipid |2 NLM | |
| 700 | 1 | |a Yuste, J R |e verfasserin |4 aut | |
| 700 | 1 | |a Páramo, J A |e verfasserin |4 aut | |
| 700 | 1 | |a Rocha, E |e verfasserin |4 aut | |
| 700 | 1 | |a Prieto, J |e verfasserin |4 aut | |
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