Serum levels of vitamins A, C and E in the population of Slovakia
BACKGROUND: Significant forms of vitamin deficiencies are rare in Slovak Republic, however mild hypovitaminoses are still relatively frequent and they have negative consequences on the functional status. Vitamins A, C and E represent an important part of the antioxidant defense system acting against free-radical damage. Imbalance between oxidative stress and antioxidant capacity which leads to free radical damage is considered to be an aetiological factor of ischaemic heart disease and cancer.
OBJECTIVES: The study was focused on assessment of serum levels of vitamins A, C and E in the Slovak population older than 35 y and frequency of decreased levels. Relationship between high prevalence of chronic non-communicable diseases and high frequency of suboptimal levels of antioxidant vitamins is discussed.
METHODS: Serum levels of vitamin A and E were assessed by the HPLC method, the levels of vitamin C by the colorimetric method.
RESULTS: Mean levels of vitamin A were 1.85 mumol/l in both sexes (95% c.i. 1.75-1.89 in males, 1.77-1.92 in females). Mean level of vitamin C was 31.36 mumol/l in males (95% c.i. 30.06-32.72), the value observed in females was significantly higher (43.05 mumol/l, 95% c.i. 41.75-44.40). Mean level of vitamin E observed in males (29.2 mumol/l, 95% c.i. 27.62-30.87) was only slightly, not significantly higher than in females (28.11 mumol/l, 95% c.i. 26.45-29.87). Decreased levels of vitamin E were observed only in a small proportion of the sample, however almost one third of males had decreased level of vitamin C and more than 20% had low level of vitamin A. We observed high prevalence of serum levels of vitamins A, C and E suboptimal from the aspect of risk of coronary heart disease and cancer (vitamin A: males 78%, females 75.5%, vitamin E: 41.9 and 49.6%, respectively, vitamin C: 61.8% and 41.1%).
CONCLUSION: Results indicate that sizeable proportion of population has decreased serum levels of vitamins, males especially of vitamin C and females of vitamin A. According to serum levels of vitamin A, C and E high percentage of population can be ranked into the group with increased risk of CHD and cancer. (Tab. 6, Ref. 29.).
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
1995 |
|---|---|
| Erschienen: |
1995 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:96 |
|---|---|
| Enthalten in: |
Bratislavske lekarske listy - 96(1995), 8 vom: 16. Aug., Seite 430-4 |
| Sprache: |
Slowakisch |
|---|
| Weiterer Titel: |
Sérové hladiny vitamínov A, C a E u obyvatel'ov Slovenska |
|---|
| Beteiligte Personen: |
Babinská, K [VerfasserIn] |
|---|
| Themen: |
11103-57-4 |
|---|
| Anmerkungen: |
Date Completed 28.02.1996 Date Revised 26.10.2016 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM085305715 |
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| 245 | 1 | 0 | |a Serum levels of vitamins A, C and E in the population of Slovakia |
| 246 | 3 | 3 | |a Sérové hladiny vitamínov A, C a E u obyvatel'ov Slovenska |
| 264 | 1 | |c 1995 | |
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| 500 | |a Date Completed 28.02.1996 | ||
| 500 | |a Date Revised 26.10.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Significant forms of vitamin deficiencies are rare in Slovak Republic, however mild hypovitaminoses are still relatively frequent and they have negative consequences on the functional status. Vitamins A, C and E represent an important part of the antioxidant defense system acting against free-radical damage. Imbalance between oxidative stress and antioxidant capacity which leads to free radical damage is considered to be an aetiological factor of ischaemic heart disease and cancer | ||
| 520 | |a OBJECTIVES: The study was focused on assessment of serum levels of vitamins A, C and E in the Slovak population older than 35 y and frequency of decreased levels. Relationship between high prevalence of chronic non-communicable diseases and high frequency of suboptimal levels of antioxidant vitamins is discussed | ||
| 520 | |a METHODS: Serum levels of vitamin A and E were assessed by the HPLC method, the levels of vitamin C by the colorimetric method | ||
| 520 | |a RESULTS: Mean levels of vitamin A were 1.85 mumol/l in both sexes (95% c.i. 1.75-1.89 in males, 1.77-1.92 in females). Mean level of vitamin C was 31.36 mumol/l in males (95% c.i. 30.06-32.72), the value observed in females was significantly higher (43.05 mumol/l, 95% c.i. 41.75-44.40). Mean level of vitamin E observed in males (29.2 mumol/l, 95% c.i. 27.62-30.87) was only slightly, not significantly higher than in females (28.11 mumol/l, 95% c.i. 26.45-29.87). Decreased levels of vitamin E were observed only in a small proportion of the sample, however almost one third of males had decreased level of vitamin C and more than 20% had low level of vitamin A. We observed high prevalence of serum levels of vitamins A, C and E suboptimal from the aspect of risk of coronary heart disease and cancer (vitamin A: males 78%, females 75.5%, vitamin E: 41.9 and 49.6%, respectively, vitamin C: 61.8% and 41.1%) | ||
| 520 | |a CONCLUSION: Results indicate that sizeable proportion of population has decreased serum levels of vitamins, males especially of vitamin C and females of vitamin A. According to serum levels of vitamin A, C and E high percentage of population can be ranked into the group with increased risk of CHD and cancer. (Tab. 6, Ref. 29.) | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Vitamin A |2 NLM | |
| 650 | 7 | |a 11103-57-4 |2 NLM | |
| 650 | 7 | |a Vitamin E |2 NLM | |
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| 700 | 1 | |a Magálová, T |e verfasserin |4 aut | |
| 700 | 1 | |a Brtková, A |e verfasserin |4 aut | |
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