Draining sinus in acne and rosacea. A clinical, histopathologic and experimental study
The draining sinus is an unpleasant complication of acne conglobata, acne fulminans, acne inversa, rosacea conglobata and rosacea fulminans (pyoderma faciale). It is most common on the face, especially in the nasolabial folds, and on the neck below the mandibular line. Clinically, it is an elongated (2-5 cm long), elevated, periodically inflamed lesion, which sporadically discharges pus. The lesion persists with no tendency to spontaneous regression. Histopathologically, it consists of elaborate, epithelialized galleries connected to the skin surface at multiple points. It contains corneocytes, hairs, bacteria, serum, inflammatory cells and epitheloid granulomas. A surgical thread placed into the skin provides a model in which the generation of sinus tracts can be studied. Therapy is difficult. Intralesional corticosteroid injection, cryosurgery and isotretinoin are not always very effective. Sometimes complete excision of the lesion is necessary. The draining sinus is a special form of scar analogous to the pilonidal cyst.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1995 |
|---|---|
| Erschienen: |
1995 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
|---|---|
| Enthalten in: |
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - 46(1995), 6 vom: 20. Juni, Seite 417-20 |
| Sprache: |
Deutsch |
|---|
| Weiterer Titel: |
Abszedierende Fistelgänge bei Akne und Rosazea. Eine klinische, histopathologische und experimentelle Untersuchung |
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| Beteiligte Personen: |
Jansen, T [VerfasserIn] |
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| Themen: |
Adrenal Cortex Hormones |
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| Anmerkungen: |
Date Completed 21.09.1995 Date Revised 20.09.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM076183696 |
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| 245 | 1 | 0 | |a Draining sinus in acne and rosacea. A clinical, histopathologic and experimental study |
| 246 | 3 | 3 | |a Abszedierende Fistelgänge bei Akne und Rosazea. Eine klinische, histopathologische und experimentelle Untersuchung |
| 264 | 1 | |c 1995 | |
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| 500 | |a Date Completed 21.09.1995 | ||
| 500 | |a Date Revised 20.09.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The draining sinus is an unpleasant complication of acne conglobata, acne fulminans, acne inversa, rosacea conglobata and rosacea fulminans (pyoderma faciale). It is most common on the face, especially in the nasolabial folds, and on the neck below the mandibular line. Clinically, it is an elongated (2-5 cm long), elevated, periodically inflamed lesion, which sporadically discharges pus. The lesion persists with no tendency to spontaneous regression. Histopathologically, it consists of elaborate, epithelialized galleries connected to the skin surface at multiple points. It contains corneocytes, hairs, bacteria, serum, inflammatory cells and epitheloid granulomas. A surgical thread placed into the skin provides a model in which the generation of sinus tracts can be studied. Therapy is difficult. Intralesional corticosteroid injection, cryosurgery and isotretinoin are not always very effective. Sometimes complete excision of the lesion is necessary. The draining sinus is a special form of scar analogous to the pilonidal cyst | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Adrenal Cortex Hormones |2 NLM | |
| 650 | 7 | |a Isotretinoin |2 NLM | |
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