Clinical aspects of parathyroid hypertensive factor
To determine the clinical significance of parathyroid hypertensive factor (PHF), physiological studies previously performed in animal models of hypertension were parallelled by human studies. These studies revealed that PHF-like activity is present in human hypertension, where it correlates with the salt-sensitive, low-renin state. As in spontaneously hypertensive rats, both supplemental calcium and calcium-channel blockers appear to be useful in the treatment of PHF-related hypertension. In primary hyperparathyroid patients, PHF presence is linked with the presence of hypertension. Postparathyroidectomy blood pressure falls in parallel with PHF levels. These preliminary human studies suggest that PHF may be a useful marker in the treatment of hypertension.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1994 |
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| Erschienen: |
1994 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 Suppl 2 |
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| Enthalten in: |
Journal of cardiovascular pharmacology - 23 Suppl 2(1994) vom: 22., Seite S23-6 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Lewanczuk, R Z [VerfasserIn] |
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| Themen: |
Biological Factors |
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| Anmerkungen: |
Date Completed 15.08.1994 Date Revised 16.11.2005 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM074946307 |
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| 100 | 1 | |a Lewanczuk, R Z |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical aspects of parathyroid hypertensive factor |
| 264 | 1 | |c 1994 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Completed 15.08.1994 | ||
| 500 | |a Date Revised 16.11.2005 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a To determine the clinical significance of parathyroid hypertensive factor (PHF), physiological studies previously performed in animal models of hypertension were parallelled by human studies. These studies revealed that PHF-like activity is present in human hypertension, where it correlates with the salt-sensitive, low-renin state. As in spontaneously hypertensive rats, both supplemental calcium and calcium-channel blockers appear to be useful in the treatment of PHF-related hypertension. In primary hyperparathyroid patients, PHF presence is linked with the presence of hypertension. Postparathyroidectomy blood pressure falls in parallel with PHF levels. These preliminary human studies suggest that PHF may be a useful marker in the treatment of hypertension | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Biological Factors |2 NLM | |
| 650 | 7 | |a Calcium Channel Blockers |2 NLM | |
| 650 | 7 | |a Calcium, Dietary |2 NLM | |
| 650 | 7 | |a parathyroid hypertensive factor |2 NLM | |
| 700 | 1 | |a Benishin, C G |e verfasserin |4 aut | |
| 700 | 1 | |a Shan, J |e verfasserin |4 aut | |
| 700 | 1 | |a Pang, P K |e verfasserin |4 aut | |
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