Ultrasound detection of uterine abnormalities after diethylstilbestrol (DES) exposure

Diethylstilbestrol (DES) was widely prescribed to pregnant women from 1940 to 1960. This resulted in multiple benign abnormalities of the genital tract and occasional malignant transformation in women who had been exposed to DES in utero. Over 300 cases of clear cell adenocarcinoma of the vagina have been described to date. In this study, 18 DES-exposed women and 20 normal age-matched controls were studied with ultrasound. An estimated uterine volume of 49.4 cm3 +/- 25.5 SD was found in the exposed subjects, compared with 90 cm3 +/- 22 SD in the normal subjects. Three out of 18 women (16%) had a T-shaped uterus. Ultrasound can detect some of the uterine abnormalities which occur due to DES exposure.

Medienart:

Artikel

Erscheinungsjahr:

1980

Erschienen:

1980

Enthalten in:

Zur Gesamtaufnahme - volume:136

Enthalten in:

Radiology - 136(1980), 3 vom: 14. Sept., Seite 733-5

Sprache:

Englisch

Beteiligte Personen:

Viscomi, G N [VerfasserIn]
Gonzalez, R [VerfasserIn]
Taylor, K J [VerfasserIn]

Themen:

731DCA35BT
Biology
Clinical Research
Diethylstilbestrol
Diethylstilbestrol--side effects
Endocrine System
Estrogens
Examinations And Diagnoses
Genitalia
Genitalia, Female
Hormones
Journal Article
Physiology
Research Methodology
Ultrasonics
Urogenital System
Uterine Effects
Uterus
Women

Anmerkungen:

Date Completed 27.10.1980

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM073802026