Tobacco mosaic virus protein induces fusion of liposome membranes

The fusogenic properties of tobacco mosaic virus (TMV) coat protein were investigated. Tobacco mosaic virus protein induces membrane fusion of a population of L-alpha-dimyristoylphosphatidylcholine (DMPC) and DL-alpha-dipalmitoylphosphatidylcholine (DPPC) vesicles giving rise to larger particles as seen by a drastic absorbance increase of the liposomal solution. Differential scanning calorimetry spectra demonstrate complete mixing of the acyl chains of the lipids during fusion. Electron micrographs indicate that the fused entities are multilamellar.

Medienart:

Artikel

Erscheinungsjahr:

1981

Erschienen:

1981

Enthalten in:

Zur Gesamtaufnahme - volume:646

Enthalten in:

Biochimica et biophysica acta - 646(1981), 2 vom: 20. Aug., Seite 360-4

Sprache:

Englisch

Beteiligte Personen:

Banerjee, S [VerfasserIn]
Vandenbranden, M [VerfasserIn]
Ruysschaert, J M [VerfasserIn]

Themen:

Dimyristoylphosphatidylcholine
Journal Article
Liposomes
Phosphatidylcholines
Pulmonary Surfactants
Research Support, Non-U.S. Gov't
U86ZGC74V5
Viral Proteins

Anmerkungen:

Date Completed 20.01.1982

Date Revised 10.06.2019

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM068721587