Detection of inapparent forms of hepatitis in foci of the infection by using sensitive methods of specific diagnosis
The use of specific sensitive methods for demonstration of hepatitis A markers has made it possible to detect 6 children with inapparent form of the disease among 86 subjects present in the focus of infection. Specific HAV antibody of the M class were detected in 100% of them. By radioimmunoassay, hepatitis A virus antigen (HAV-Ag) was detected in fecal extracts in 1 case only. Liver biopsy from 1 patient with inapparent disease showed typical morphological signs of acute hepatitis, and HAV-Ag was detected in the hepatocyte cytoplasm by immunofluorescence. Titres of specific antibody in convalescence varied from 1:10 to 1:800 in patients with the inapparent forms and from 1:200 to 1:3200 in manifest forms of hepatitis A.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1985 |
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| Erschienen: |
1985 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
|---|---|
| Enthalten in: |
Voprosy virusologii - 30(1985), 3 vom: 30. Mai, Seite 333-7 |
| Sprache: |
Russisch |
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| Weiterer Titel: |
Vyiavlenie inapparantnykh form gepatita v ochagakh infektsii s pomoshch'iu chuvstvitel'nykh metodov spetsificheskoĭ diagnostiki |
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| Beteiligte Personen: |
Doroshenko, N V [VerfasserIn] |
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| Themen: |
English Abstract |
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| Anmerkungen: |
Date Completed 04.11.1985 Date Revised 09.11.2016 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM040310914 |
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| 100 | 1 | |a Doroshenko, N V |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Detection of inapparent forms of hepatitis in foci of the infection by using sensitive methods of specific diagnosis |
| 246 | 3 | 3 | |a Vyiavlenie inapparantnykh form gepatita v ochagakh infektsii s pomoshch'iu chuvstvitel'nykh metodov spetsificheskoĭ diagnostiki |
| 264 | 1 | |c 1985 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 04.11.1985 | ||
| 500 | |a Date Revised 09.11.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The use of specific sensitive methods for demonstration of hepatitis A markers has made it possible to detect 6 children with inapparent form of the disease among 86 subjects present in the focus of infection. Specific HAV antibody of the M class were detected in 100% of them. By radioimmunoassay, hepatitis A virus antigen (HAV-Ag) was detected in fecal extracts in 1 case only. Liver biopsy from 1 patient with inapparent disease showed typical morphological signs of acute hepatitis, and HAV-Ag was detected in the hepatocyte cytoplasm by immunofluorescence. Titres of specific antibody in convalescence varied from 1:10 to 1:800 in patients with the inapparent forms and from 1:200 to 1:3200 in manifest forms of hepatitis A | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Hepatitis Antibodies |2 NLM | |
| 650 | 7 | |a Immunoglobulin M |2 NLM | |
| 700 | 1 | |a Zhylkylbaev, E Zh |e verfasserin |4 aut | |
| 700 | 1 | |a Zhilina, N N |e verfasserin |4 aut | |
| 700 | 1 | |a Kelli, E I |e verfasserin |4 aut | |
| 700 | 1 | |a Braginskiĭ, D M |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Voprosy virusologii |d 1956 |g 30(1985), 3 vom: 30. Mai, Seite 333-7 |w (DE-627)NLM000024201 |x 2411-2097 |7 nnns |
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