Evidence that SE is distal to LU on chromosome 19q

Analysis of a family informative for chromosome 19 loci establishes that the Lutheran blood group locus (LU) lies between the third component of human complement (C3) and the secretor loci (SE). Previously published lod scores for C3:LU are increased from 2.94 to 3.80. The linkage relationships (zeta and theta) between C3, LU, and SE are examined, and the proposed order and approximate genetic distances are determined to be: pter--C3-10.6cM-cen-7.4cM-LU-9cM-SE--qter.

Medienart:

Artikel

Erscheinungsjahr:

1989

Erschienen:

1989

Enthalten in:

Zur Gesamtaufnahme - volume:29

Enthalten in:

Transfusion - 29(1989), 4 vom: 15. Mai, Seite 304-5

Sprache:

Englisch

Beteiligte Personen:

Zelinski, T [VerfasserIn]
Coghlan, G [VerfasserIn]
Greenberg, C R [VerfasserIn]
McAlpine, P J [VerfasserIn]
Lewis, M [VerfasserIn]

Themen:

Complement C3
Journal Article
Lewis Blood Group Antigens
Lutheran Blood-Group System
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 16.06.1989

Date Revised 10.12.2019

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM02699559X