Presence of gamma interferon in human acute and congenital toxoplasmosis
The production of gamma interferon in acute acquired and congenital toxoplasmosis was studied. Gamma interferon was produced at significant titers (P less than 0.001) in the course of both congenital toxoplasmosis and acquired toxoplasmosis at an early stage of infection, when Toxoplasma gondii was multiplying. Its presence in fetal blood was correlated with the positive inoculation of fetal blood or amniotic fluid into mice (95%). The data suggest that the fetus is able to synthesize gamma interferon as early as week 21 of pregnancy. This test, easily and rapidly performed, could be included among those useful for diagnosing fetal toxoplasmic disease.
Errataetall: | |
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Medienart: |
Artikel |
Erscheinungsjahr: |
1990 |
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Erschienen: |
1990 |
Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
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Enthalten in: |
Journal of clinical microbiology - 28(1990), 6 vom: 16. Juni, Seite 1434-7 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Raymond, J [VerfasserIn] |
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Themen: |
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Anmerkungen: |
Date Completed 12.09.1990 Date Revised 26.05.2021 published: Print ErratumIn: J Clin Microbiol 1990 Dec;28(12):2853 Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM020978294 |
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245 | 1 | 0 | |a Presence of gamma interferon in human acute and congenital toxoplasmosis |
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500 | |a Date Completed 12.09.1990 | ||
500 | |a Date Revised 26.05.2021 | ||
500 | |a published: Print | ||
500 | |a ErratumIn: J Clin Microbiol 1990 Dec;28(12):2853 | ||
500 | |a Citation Status MEDLINE | ||
520 | |a The production of gamma interferon in acute acquired and congenital toxoplasmosis was studied. Gamma interferon was produced at significant titers (P less than 0.001) in the course of both congenital toxoplasmosis and acquired toxoplasmosis at an early stage of infection, when Toxoplasma gondii was multiplying. Its presence in fetal blood was correlated with the positive inoculation of fetal blood or amniotic fluid into mice (95%). The data suggest that the fetus is able to synthesize gamma interferon as early as week 21 of pregnancy. This test, easily and rapidly performed, could be included among those useful for diagnosing fetal toxoplasmic disease | ||
650 | 4 | |a Journal Article | |
650 | 7 | |a Biomarkers |2 NLM | |
650 | 7 | |a Interferon-gamma |2 NLM | |
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700 | 1 | |a Poissonnier, M H |e verfasserin |4 aut | |
700 | 1 | |a Thulliez, P H |e verfasserin |4 aut | |
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700 | 1 | |a Daffos, F |e verfasserin |4 aut | |
700 | 1 | |a Lebon, P |e verfasserin |4 aut | |
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