Presence of gamma interferon in human acute and congenital toxoplasmosis

The production of gamma interferon in acute acquired and congenital toxoplasmosis was studied. Gamma interferon was produced at significant titers (P less than 0.001) in the course of both congenital toxoplasmosis and acquired toxoplasmosis at an early stage of infection, when Toxoplasma gondii was multiplying. Its presence in fetal blood was correlated with the positive inoculation of fetal blood or amniotic fluid into mice (95%). The data suggest that the fetus is able to synthesize gamma interferon as early as week 21 of pregnancy. This test, easily and rapidly performed, could be included among those useful for diagnosing fetal toxoplasmic disease.

Errataetall:

ErratumIn: J Clin Microbiol 1990 Dec;28(12):2853

Medienart:

Artikel

Erscheinungsjahr:

1990

Erschienen:

1990

Enthalten in:

Zur Gesamtaufnahme - volume:28

Enthalten in:

Journal of clinical microbiology - 28(1990), 6 vom: 16. Juni, Seite 1434-7

Sprache:

Englisch

Beteiligte Personen:

Raymond, J [VerfasserIn]
Poissonnier, M H [VerfasserIn]
Thulliez, P H [VerfasserIn]
Forestier, F [VerfasserIn]
Daffos, F [VerfasserIn]
Lebon, P [VerfasserIn]

Themen:

82115-62-6
Biomarkers
Interferon-gamma
Journal Article

Anmerkungen:

Date Completed 12.09.1990

Date Revised 26.05.2021

published: Print

ErratumIn: J Clin Microbiol 1990 Dec;28(12):2853

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM020978294