The immunomodulating properties of a macro glycopeptide isolated from serum. II. The activation of macrophages and polymorphonuclear cells
The stimulating properties of three fractions of a glucomacropeptide consisting of different carbohydrate and peptide components were studied. The phagocytic activity of polymorphonuclears was increased on the 24th hour and of macrophages on the 3rd day after application of the preparations to mice. In vitro fraction 3 stimulates the lysozyme activity and the synthesis of proteins and Clq of the macrophages complement. These properties of the cells are collaborated by the established ultrastructural changes. The different composition of the fractions determines their immunostimulating effect.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
1990 |
|---|---|
| Erschienen: |
1990 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
|---|---|
| Enthalten in: |
Acta microbiologica Bulgarica - 26(1990) vom: 15., Seite 19-25 |
| Sprache: |
Bulgarisch |
|---|
| Weiterer Titel: |
Imunomodulirashti svoĭstva na gliukomakropeptid, izoliran ot surovatka. II. Aktivirane na makrofagi i polimorfonukleari |
|---|
| Beteiligte Personen: |
Neĭchev, Kh [VerfasserIn] |
|---|
| Themen: |
80295-33-6 |
|---|
| Anmerkungen: |
Date Completed 24.07.1991 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
NLM020792727 |
|---|
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| 100 | 1 | |a Neĭchev, Kh |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The immunomodulating properties of a macro glycopeptide isolated from serum. II. The activation of macrophages and polymorphonuclear cells |
| 246 | 3 | 3 | |a Imunomodulirashti svoĭstva na gliukomakropeptid, izoliran ot surovatka. II. Aktivirane na makrofagi i polimorfonukleari |
| 264 | 1 | |c 1990 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 24.07.1991 | ||
| 500 | |a Date Revised 15.11.2006 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The stimulating properties of three fractions of a glucomacropeptide consisting of different carbohydrate and peptide components were studied. The phagocytic activity of polymorphonuclears was increased on the 24th hour and of macrophages on the 3rd day after application of the preparations to mice. In vitro fraction 3 stimulates the lysozyme activity and the synthesis of proteins and Clq of the macrophages complement. These properties of the cells are collaborated by the established ultrastructural changes. The different composition of the fractions determines their immunostimulating effect | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Adjuvants, Immunologic |2 NLM | |
| 650 | 7 | |a Glycopeptides |2 NLM | |
| 650 | 7 | |a Macromolecular Substances |2 NLM | |
| 650 | 7 | |a Peptide Fragments |2 NLM | |
| 650 | 7 | |a Complement C1q |2 NLM | |
| 650 | 7 | |a 80295-33-6 |2 NLM | |
| 650 | 7 | |a Muramidase |2 NLM | |
| 650 | 7 | |a EC 3.2.1.17 |2 NLM | |
| 700 | 1 | |a Ivanovska, N |e verfasserin |4 aut | |
| 700 | 1 | |a Shirova, L |e verfasserin |4 aut | |
| 700 | 1 | |a Slavcheva, E |e verfasserin |4 aut | |
| 700 | 1 | |a Stoianova, P |e verfasserin |4 aut | |
| 700 | 1 | |a Georgiev, D |e verfasserin |4 aut | |
| 700 | 1 | |a Abrashev, I |e verfasserin |4 aut | |
| 700 | 1 | |a Velcheva, P |e verfasserin |4 aut | |
| 700 | 1 | |a Ianchev, I |e verfasserin |4 aut | |
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