Heparin effect on prevention of pelvic adhesions. Experimental study

Thirty-one mongrel female dogs were submitted to a standard lesion on the right uterine horn, consisting of crushing, scratching, and ischemia of the segment. Three groups were formed for the study: control group (GC), experimental group I (G1), and experimental group II (G2). In GC, continuous washing with simple ringer solution was applied during surgery. In G1, heparin was added to the ringer solution at a doses of 100 IU/kg. In G2, in addition to the heparin diluted in the ringer solution, subcutaneous heparin was given at 12 hours intervals for three days, at a doses of 100 IU/kg/doses. The percentage of dogs with pelvic adhesions was determined by laparotomy. Adhesion intensity in the incision and in the pelvis was determined. 100% of dogs in G2 had adhesions in the incision, whereas 66.66% had incision adhesion in GC. There was no statistical difference. All groups presented around 50% of pelvic adhesions. Intensity of pelvic adhesions was not different in the three groups, but G2 had more adhesions than GC, such difference being statistically significant.

Medienart:

Artikel

Erscheinungsjahr:

1991

Erschienen:

1991

Enthalten in:

Zur Gesamtaufnahme - volume:109

Enthalten in:

Revista paulista de medicina - 109(1991), 6 vom: 04. Nov., Seite 247-51

Sprache:

Portugiesisch

Weiterer Titel:

Efeito da heparina na prevenção de aderências pélvicas. Estudo experimental

Beteiligte Personen:

Florêncio, R de S [VerfasserIn]
Baracat, E C [VerfasserIn]
Focchi, J [VerfasserIn]
de Lima, G R [VerfasserIn]

Themen:

9005-49-6
Comparative Study
English Abstract
Heparin
Journal Article
Solutions

Anmerkungen:

Date Completed 03.08.1992

Date Revised 21.11.2008

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM018019730