Onset of obsessive-compulsive disorder in pregnancy

OBJECTIVE: Although the role of pregnancy and childbirth in postpartum psychosis and depression has been studied, the association between pregnancy and obsessive-compulsive disorder has not been specifically addressed. The authors evaluated the role of pregnancy in the onset of obsessive-compulsive disorder.

METHOD: Female patients with obsessive-compulsive disorder (N = 106) completed a questionnaire assessing age at onset of symptoms, marital status, number of children, age at each pregnancy, and life events associated with the onset of obsessive-compulsive disorder.

RESULTS: Of the 106 women, 42 were childless and 59 had at least one child each; five others were also childless but had had abortions (N = 4) or a miscarriage (N = 1). Of the 42 women without children, 12 (28.6%) had first experienced obsessive-compulsive symptoms between the ages of 13 and 15 years, but there were two peaks of onset for the women with children: ages 22-24 and 29-32 years. Of the 59 patients with children, 23 (39.0%) had experienced symptom onset during pregnancy; this was the first pregnancy for 12, the second pregnancy for eight, and the third pregnancy for three. Four of the five women who had had abortions or a miscarriage had experienced the onset or an exacerbation of obsessive-compulsive symptoms during pregnancy.

CONCLUSIONS: The association between pregnancy and the onset of obsessive-compulsive symptoms in these female patients highlights the need for further research on psychological and biological factors associated with pregnancy and obsessive-compulsive disorder.

Errataetall:

CommentIn: Am J Psychiatry. 1993 Jul;150(7):1131-2. - PMID 8317598

Medienart:

Artikel

Erscheinungsjahr:

1992

Erschienen:

1992

Enthalten in:

Zur Gesamtaufnahme - volume:149

Enthalten in:

The American journal of psychiatry - 149(1992), 7 vom: 15. Juli, Seite 947-50

Sprache:

Englisch

Beteiligte Personen:

Neziroglu, F [VerfasserIn]
Anemone, R [VerfasserIn]
Yaryura-Tobias, J A [VerfasserIn]

Themen:

Age Factors
Behavior
Data Collection
Demographic Factors
Diseases
Journal Article
Population
Population Characteristics
Postpartum Women
Pregnancy
Psychological Factors
Puerperium
Reproduction
Research Methodology
Signs And Symptoms
Stress

Anmerkungen:

Date Completed 21.07.1992

Date Revised 17.11.2004

published: Print

CommentIn: Am J Psychiatry. 1993 Jul;150(7):1131-2. - PMID 8317598

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM015913686