Dengue haemorrhagic fever in children in Delhi
An epidemic of dengue haemorrhagic fever occurred in Delhi during 1988. A total of 21 paediatric patients with dengue haemorrhagic fever/dengue shock syndrome were evaluated from September to November 1988. All the patients had fever, restlessness, ecchymotic spots and ascites. Pleural effusion occurred in 19 patients (90%), and 18 (86%) exhibited each of the following: vomiting, thrombocytopenia, and haemoconcentration. Hepatomegaly was observed in 15 patients (71%) and splenomegaly in three (14%). Titres of haemagglutination inhibition (HI) antibodies against dengue virus type 2 were raised in all the 15 cases from whom sera were collected during the acute stage. Convalescent sera from five patients had increased titres of HI antibodies to dengue virus type 2. The remaining 10 cases exhibited raised IgM antibody levels against dengue virus type 2. The fatality rate for serologically proven cases was 13% (2 of 15 patients), while for all patients (including those diagnosed clinically (6) and serologically (15)) it was 33.3% (7 of 21). Patients who survived had no sequelae, except one who had transient hypertension that lasted for two weeks.
Medienart: |
Artikel |
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Erscheinungsjahr: |
1992 |
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Erschienen: |
1992 |
Enthalten in: |
Zur Gesamtaufnahme - volume:70 |
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Enthalten in: |
Bulletin of the World Health Organization - 70(1992), 1 vom: 15., Seite 105-8 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Kabra, S K [VerfasserIn] |
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Anmerkungen: |
Date Completed 28.05.1992 Date Revised 13.11.2018 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM015497674 |
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100 | 1 | |a Kabra, S K |e verfasserin |4 aut | |
245 | 1 | 0 | |a Dengue haemorrhagic fever in children in Delhi |
264 | 1 | |c 1992 | |
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500 | |a Date Completed 28.05.1992 | ||
500 | |a Date Revised 13.11.2018 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a An epidemic of dengue haemorrhagic fever occurred in Delhi during 1988. A total of 21 paediatric patients with dengue haemorrhagic fever/dengue shock syndrome were evaluated from September to November 1988. All the patients had fever, restlessness, ecchymotic spots and ascites. Pleural effusion occurred in 19 patients (90%), and 18 (86%) exhibited each of the following: vomiting, thrombocytopenia, and haemoconcentration. Hepatomegaly was observed in 15 patients (71%) and splenomegaly in three (14%). Titres of haemagglutination inhibition (HI) antibodies against dengue virus type 2 were raised in all the 15 cases from whom sera were collected during the acute stage. Convalescent sera from five patients had increased titres of HI antibodies to dengue virus type 2. The remaining 10 cases exhibited raised IgM antibody levels against dengue virus type 2. The fatality rate for serologically proven cases was 13% (2 of 15 patients), while for all patients (including those diagnosed clinically (6) and serologically (15)) it was 33.3% (7 of 21). Patients who survived had no sequelae, except one who had transient hypertension that lasted for two weeks | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Age Factors | |
650 | 4 | |a Antibodies | |
650 | 4 | |a Asia | |
650 | 4 | |a Biology | |
650 | 4 | |a Child | |
650 | 4 | |a Child Mortality | |
650 | 4 | |a Demographic Factors | |
650 | 4 | |a Developing Countries | |
650 | 4 | |a Diseases | |
650 | 4 | |a Examinations And Diagnoses | |
650 | 4 | |a Immunity | |
650 | 4 | |a Immunologic Factors | |
650 | 4 | |a Incidence | |
650 | 4 | |a India | |
650 | 4 | |a Laboratory Examinations And Diagnoses | |
650 | 4 | |a Measurement | |
650 | 4 | |a Mortality | |
650 | 4 | |a Physiology | |
650 | 4 | |a Population | |
650 | 4 | |a Population Characteristics | |
650 | 4 | |a Population Dynamics | |
650 | 4 | |a Research Methodology | |
650 | 4 | |a Signs And Symptoms | |
650 | 4 | |a Southern Asia | |
650 | 4 | |a Treatment | |
650 | 4 | |a Viral Diseases | |
650 | 4 | |a Youth | |
650 | 7 | |a Antibodies, Viral |2 NLM | |
700 | 1 | |a Verma, I C |e verfasserin |4 aut | |
700 | 1 | |a Arora, N K |e verfasserin |4 aut | |
700 | 1 | |a Jain, Y |e verfasserin |4 aut | |
700 | 1 | |a Kalra, V |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Bulletin of the World Health Organization |d 1948 |g 70(1992), 1 vom: 15., Seite 105-8 |w (DE-627)NLM000211265 |x 1564-0604 |7 nnns |
773 | 1 | 8 | |g volume:70 |g year:1992 |g number:1 |g day:15 |g pages:105-8 |
912 | |a GBV_USEFLAG_A | ||
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951 | |a AR | ||
952 | |d 70 |j 1992 |e 1 |b 15 |h 105-8 |