Testicular circulatory isolation : a phase I study
Antineoplastic agents may damage germinal epithelium. Testicular circulatory isolation (TCI) is a regional drug exclusion technique designed to minimize this. We evaluated the technical and anaesthetic aspects of TCI in 10 patients who underwent bilateral orchiectomy immediately thereafter. A modified aortic clamp was placed trans-scrotally across the left testicular pedicle without pre-medication or anaesthesia and left in place for 1 h, occluding testicular blood flow. Minimal pain and anxiety were reported during the procedure. There were no complications related to TCI in any patient. This study supports the institution of trials of TCI in young men about to receive fertility-threatening chemotherapy.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1992 |
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| Erschienen: |
1992 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:1 |
|---|---|
| Enthalten in: |
Surgical oncology - 1(1992), 6 vom: 15. Dez., Seite 413-6 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Gibbons, J J [VerfasserIn] |
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| Themen: |
Antineoplastic Agents |
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| Anmerkungen: |
Date Completed 13.01.1994 Date Revised 28.10.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM01322560X |
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| 100 | 1 | |a Gibbons, J J |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Testicular circulatory isolation |b a phase I study |
| 264 | 1 | |c 1992 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 13.01.1994 | ||
| 500 | |a Date Revised 28.10.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Antineoplastic agents may damage germinal epithelium. Testicular circulatory isolation (TCI) is a regional drug exclusion technique designed to minimize this. We evaluated the technical and anaesthetic aspects of TCI in 10 patients who underwent bilateral orchiectomy immediately thereafter. A modified aortic clamp was placed trans-scrotally across the left testicular pedicle without pre-medication or anaesthesia and left in place for 1 h, occluding testicular blood flow. Minimal pain and anxiety were reported during the procedure. There were no complications related to TCI in any patient. This study supports the institution of trials of TCI in young men about to receive fertility-threatening chemotherapy | ||
| 650 | 4 | |a Clinical Trial | |
| 650 | 4 | |a Clinical Trial, Phase I | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Antineoplastic Agents |2 NLM | |
| 700 | 1 | |a Parra, R O |e verfasserin |4 aut | |
| 700 | 1 | |a Andriole, G L |e verfasserin |4 aut | |
| 700 | 1 | |a Johnson, F E |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Surgical oncology |d 1997 |g 1(1992), 6 vom: 15. Dez., Seite 413-6 |w (DE-627)NLM012658448 |x 1879-3320 |7 nnns |
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| 952 | |d 1 |j 1992 |e 6 |b 15 |c 12 |h 413-6 | ||