Primary liver tumors and oral contraceptives. Results of a survey
Data on 378 (in females) and 165 (in males) cases of primary liver tumors reported by 477 hospitals in the United States during 1970 to 1975 show that in males, 91.5% of the tumors were malignant, and in females, 43.9% were malignant and 59.1% were benign. Of the 212 benign tumors in females, 96 were hepatic cell adenomas and 58 were focal nodular hyperplasias. A history of oral contraceptive use was found in nearly half of all women: 65% with benign tumors, 74% with hepatic cell adenomas, and 74% with focal nodular hyperplasias. Symptoms were more severe among users. No case of intraperitoneal bleeding was observed in nonusers. The findings confirm the suggested association between oral contraceptive use and hepatic cell adenomas and focal nodular hyperplasias.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1977 |
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| Erschienen: |
1977 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:238 |
|---|---|
| Enthalten in: |
JAMA - 238(1977), 20 vom: 14. Nov., Seite 2154-8 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Vana, J [VerfasserIn] |
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| Themen: |
Contraceptive Agents, Male |
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| Anmerkungen: |
Date Completed 29.12.1977 Date Revised 17.10.2016 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM001987755 |
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| 100 | 1 | |a Vana, J |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Primary liver tumors and oral contraceptives. Results of a survey |
| 264 | 1 | |c 1977 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 29.12.1977 | ||
| 500 | |a Date Revised 17.10.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Data on 378 (in females) and 165 (in males) cases of primary liver tumors reported by 477 hospitals in the United States during 1970 to 1975 show that in males, 91.5% of the tumors were malignant, and in females, 43.9% were malignant and 59.1% were benign. Of the 212 benign tumors in females, 96 were hepatic cell adenomas and 58 were focal nodular hyperplasias. A history of oral contraceptive use was found in nearly half of all women: 65% with benign tumors, 74% with hepatic cell adenomas, and 74% with focal nodular hyperplasias. Symptoms were more severe among users. No case of intraperitoneal bleeding was observed in nonusers. The findings confirm the suggested association between oral contraceptive use and hepatic cell adenomas and focal nodular hyperplasias | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Contraceptive Agents, Male |2 NLM | |
| 650 | 7 | |a Contraceptives, Oral |2 NLM | |
| 700 | 1 | |a Murphy, G P |e verfasserin |4 aut | |
| 700 | 1 | |a Aronoff, B L |e verfasserin |4 aut | |
| 700 | 1 | |a Baker, H W |e verfasserin |4 aut | |
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