Necrotizing angiitis of small vessels. A clinical study of 25 patients with skin biopsy (author's transl)
Necrotizing angiitis or vasculitis exhibits a wide clinical spectrum characterized by many different cutaneous manifestations. Diagnosis must be confirmed by histopathology. We studied in retrospect 25 patients whose conditions had been diagnosed by skin biopsy. Histologic examination revealed infiltration by polynuclear cells and fibrinoid necrosis of the walls of the blood vessels in the skin. The great variety of clinical manifestations and etiologies stands out in a review of the records of these patients. Necrotizing angiitis has been found associated with mixed cryoglobulinemia; administration of drugs, milliary tuberculosis, bacterial meningitis, rickettsiosis, staphylococcal sepsis, pharyngotonsillitis, and rheumatoid arthritis. Necrotizing angiitis is a group of diseases with a great variety of clinical manifestations, ranging from benign to fatal. The various entities described to date have been more like different clinical forms of the same disease that distinct conditions. In cases of necrotizing angiitis caused by basically immunological mechanisms, the walls of the blood vessels may be impaired in varying diffuse degrees. The prognosis of the disease depends on the intensity of the inflammation and its repercussions on the parenchymas of different organs. The kidney is the most susceptible organ in this case. Treatment should be directed toward the avoidance of predisposing and etiologic factors, detection of the immunological reaction, requiring careful and individual attention in every case.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1979 |
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| Erschienen: |
1979 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:72 |
|---|---|
| Enthalten in: |
Medicina clinica - 72(1979), 4 vom: 25. Feb., Seite 139-44 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Angiitis necrosante de pequeños vasos. Estudio clínico de 25 pacientes con biopsia cutánea |
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| Beteiligte Personen: |
Miquel-Collell, C [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 29.06.1979 Date Revised 19.11.2009 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM000359025 |
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| 245 | 1 | 0 | |a Necrotizing angiitis of small vessels. A clinical study of 25 patients with skin biopsy (author's transl) |
| 246 | 3 | 3 | |a Angiitis necrosante de pequeños vasos. Estudio clínico de 25 pacientes con biopsia cutánea |
| 264 | 1 | |c 1979 | |
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| 500 | |a Date Completed 29.06.1979 | ||
| 500 | |a Date Revised 19.11.2009 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Necrotizing angiitis or vasculitis exhibits a wide clinical spectrum characterized by many different cutaneous manifestations. Diagnosis must be confirmed by histopathology. We studied in retrospect 25 patients whose conditions had been diagnosed by skin biopsy. Histologic examination revealed infiltration by polynuclear cells and fibrinoid necrosis of the walls of the blood vessels in the skin. The great variety of clinical manifestations and etiologies stands out in a review of the records of these patients. Necrotizing angiitis has been found associated with mixed cryoglobulinemia; administration of drugs, milliary tuberculosis, bacterial meningitis, rickettsiosis, staphylococcal sepsis, pharyngotonsillitis, and rheumatoid arthritis. Necrotizing angiitis is a group of diseases with a great variety of clinical manifestations, ranging from benign to fatal. The various entities described to date have been more like different clinical forms of the same disease that distinct conditions. In cases of necrotizing angiitis caused by basically immunological mechanisms, the walls of the blood vessels may be impaired in varying diffuse degrees. The prognosis of the disease depends on the intensity of the inflammation and its repercussions on the parenchymas of different organs. The kidney is the most susceptible organ in this case. Treatment should be directed toward the avoidance of predisposing and etiologic factors, detection of the immunological reaction, requiring careful and individual attention in every case | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Rubiés-Prat, J |e verfasserin |4 aut | |
| 700 | 1 | |a Caralps, A |e verfasserin |4 aut | |
| 700 | 1 | |a Vidal, M T |e verfasserin |4 aut | |
| 700 | 1 | |a Mirada, A |e verfasserin |4 aut | |
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