The binding of noradrenaline to human erythrocytes
When human erythrocytes are incubated in a suspension medium containing noradrenaline, they take up noradrenaline in a reaction proceeding in two phases. In a rapid first reaction noradrenaline is bound by the cells by adsorption at pH-values above 6.0; this reaction follows Freundlich's isotherms. Subsequently, noradrenaline is taken up much more slowly by transmembranous diffusion into the cells. Neither reaction can be influenced by inhibitors such as N-ethyl maleinimide, ouabain, alpha- or beta-receptor blockers.
Medienart: |
Artikel |
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Erscheinungsjahr: |
1976 |
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Erschienen: |
1976 |
Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
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Enthalten in: |
Acta biologica et medica Germanica - 35(1976), 6 vom: 15., Seite 709-13 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Bluth, R [VerfasserIn] |
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Themen: |
Journal Article |
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Anmerkungen: |
Date Completed 23.12.1976 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
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245 | 1 | 4 | |a The binding of noradrenaline to human erythrocytes |
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500 | |a Date Revised 21.11.2013 | ||
500 | |a published: Print | ||
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520 | |a When human erythrocytes are incubated in a suspension medium containing noradrenaline, they take up noradrenaline in a reaction proceeding in two phases. In a rapid first reaction noradrenaline is bound by the cells by adsorption at pH-values above 6.0; this reaction follows Freundlich's isotherms. Subsequently, noradrenaline is taken up much more slowly by transmembranous diffusion into the cells. Neither reaction can be influenced by inhibitors such as N-ethyl maleinimide, ouabain, alpha- or beta-receptor blockers | ||
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