The binding of noradrenaline to human erythrocytes

When human erythrocytes are incubated in a suspension medium containing noradrenaline, they take up noradrenaline in a reaction proceeding in two phases. In a rapid first reaction noradrenaline is bound by the cells by adsorption at pH-values above 6.0; this reaction follows Freundlich's isotherms. Subsequently, noradrenaline is taken up much more slowly by transmembranous diffusion into the cells. Neither reaction can be influenced by inhibitors such as N-ethyl maleinimide, ouabain, alpha- or beta-receptor blockers.

Medienart:

Artikel

Erscheinungsjahr:

1976

Erschienen:

1976

Enthalten in:

Zur Gesamtaufnahme - volume:35

Enthalten in:

Acta biologica et medica Germanica - 35(1976), 6 vom: 15., Seite 709-13

Sprache:

Englisch

Beteiligte Personen:

Bluth, R [VerfasserIn]
Banaschak, H [VerfasserIn]

Themen:

Journal Article
Norepinephrine
Receptors, Cell Surface
X4W3ENH1CV

Anmerkungen:

Date Completed 23.12.1976

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM00011426X