Hypnotic efficacy of lorazepam and flurazepam
In a double-blind crossover study involving 15 insomniac subjects, the hypnotic efficacy of lorazepam, 2 and 4 mg, was compared with flurazepam, 15 and 30 mg, and placebo. Five subjective measures were used: onset, length, and depth of sleep, number of times awakened, and satisfaction with the hypnotic. Lorazepam in 2- and 4-mg doses was comparable in hypnotic efficacy to flurazepam, 30 mg, according to most parameters of measurement. Side effects were minor, although relatively numerous at the 4-mg doses.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1976 |
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| Erschienen: |
1976 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
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| Enthalten in: |
Clinical pharmacology and therapeutics - 19(1976), 2 vom: 15. Feb., Seite 191-5 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wang, R I [VerfasserIn] |
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| Themen: |
Anti-Anxiety Agents |
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| Anmerkungen: |
Date Completed 06.07.1976 Date Revised 09.05.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM000049204 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a In a double-blind crossover study involving 15 insomniac subjects, the hypnotic efficacy of lorazepam, 2 and 4 mg, was compared with flurazepam, 15 and 30 mg, and placebo. Five subjective measures were used: onset, length, and depth of sleep, number of times awakened, and satisfaction with the hypnotic. Lorazepam in 2- and 4-mg doses was comparable in hypnotic efficacy to flurazepam, 30 mg, according to most parameters of measurement. Side effects were minor, although relatively numerous at the 4-mg doses | ||
| 650 | 4 | |a Clinical Trial | |
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Controlled Clinical Trial | |
| 650 | 4 | |a Journal Article | |
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| 650 | 7 | |a Flurazepam |2 NLM | |
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| 650 | 7 | |a Lorazepam |2 NLM | |
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| 700 | 1 | |a Hieb, E |e verfasserin |4 aut | |
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