Successful Outcome After Antibiotic Treatment of Postamniocentesis MembraneRupture and Chorioamnionitis in Multiple Pregnancy

-Postamniocentesis chorioamnionitis is usually managed with induction of labor to prevent maternal sepsis and related morbidity and mortality. We report a case of chorioamnionitis in a triplet pregnancy after midtrimester genetic amniocentesis, in which multiple antibiotic treatment (ampicillin 2 g i.v. loading dose followed by 1 g i.v. every 6 hr; clindamycin 900 mg i.v. every 8 hr; gentamicin 120 mg i.v. loading dose followed by 100 mg i.v. every 8 hrs; and erythromycin 500 mg i.v. every 6 hr) for 7 days and delivery of the presumably infected triplet A successfully reversed the clinical symptomatology, allowing prolongation of pregnancy until 26 weeks and survival of the remaining fetuses. At age 2 years, both infants are doing well and are meeting their developmental milestones. The viable outcome of this management strategy suggests that antibiotic treatment and expectancy may be an option in selected cases of postamniocentesis chorioamnionitis in multiple pregnancies..

Medienart:

E-Artikel

Erscheinungsjahr:

1999

Erschienen:

Stuttgart: Georg Thieme Verlag ; 1999

Reproduktion:

Thieme Zeitschriftenarchive 1980-2007

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

American journal of perinatology - 16(1999), 08 vom: Aug., Seite 403-406

Sprache:

Englisch

Beteiligte Personen:

Ghidini, Alessandro [VerfasserIn]
Doria, Valentina [VerfasserIn]
Kirn, Valentina [VerfasserIn]
Korker, Victoria [Sonstige Person]

Links:

dx.doi.org [Deutschlandweit zugänglich]

Themen:

Amniocentesis
Cerclage
Chorioamnionitis
Multiple gestation

Umfang:

4

doi:

10.1055/s-1999-6819

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLEJ227392132