Solubility of codeine phosphate in carbitol + 2-propanol mixture at different temperatures / Homa Rezaei, Abolghasem Jouyban, Fleming Martinez, Mohammad Barzegar-Jalali, Elaheh Rahimpour
Abstract The solubility profile of codeine phosphate in the carbitol and 2-propanol mixtures at 293.2–313.2 K are determined and correlated with some developed cosolvency models. Moreover, the density values of codeine phosphate saturated solutions are also determined and fitted with the Jouyban–Acree model. The model accuracy is investigated by calculating the mean relative deviations (MRDs%). The thermodynamic parameters of codeine phosphate dissolution in the non-aqueous mixtures of carbitol and 2-propanol are also computed by using van’t Hoff and Gibbs equations.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
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| Enthalten in: |
Drug development and industrial pharmacy - 46(2020), 6, Seite 910-915 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rezaei, Homa [VerfasserIn] |
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| Links: |
FID Access [lizenzpflichtig] |
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| Themen: |
2-propanol |
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| Umfang: |
1 Online-Ressource (6 p) |
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| doi: |
10.1080/03639045.2020.1762203 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
KFL01118793X |
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| 245 | 1 | 0 | |a Solubility of codeine phosphate in carbitol + 2-propanol mixture at different temperatures |c Homa Rezaei, Abolghasem Jouyban, Fleming Martinez, Mohammad Barzegar-Jalali, Elaheh Rahimpour |
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| 520 | |a Abstract The solubility profile of codeine phosphate in the carbitol and 2-propanol mixtures at 293.2–313.2 K are determined and correlated with some developed cosolvency models. Moreover, the density values of codeine phosphate saturated solutions are also determined and fitted with the Jouyban–Acree model. The model accuracy is investigated by calculating the mean relative deviations (MRDs%). The thermodynamic parameters of codeine phosphate dissolution in the non-aqueous mixtures of carbitol and 2-propanol are also computed by using van’t Hoff and Gibbs equations | ||
| 653 | |a Solubility | ||
| 653 | |a codeine phosphate | ||
| 653 | |a carbitol | ||
| 653 | |a 2-propanol | ||
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| 700 | 1 | |a Barzegar-Jalali, Mohammad |e verfasserin |4 aut | |
| 700 | 1 | |a Rahimpour, Elaheh |e verfasserin |4 aut | |
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