An Overview of the Synthetic Route to the Marketed Formulations of Pyrimidine: A Review / Amit Kumar, Ankit Siwach, Prabhakar Verma
Pyrimidine and its derivatives are a very important class of heterocyclic compounds that show interesting applications in the field of medicinal chemistry. Pyrimidine not only plays an important role as an organic reaction intermediate but also has a wide range of interesting biological activities viz. antibacterial, antifungal, anticancer, anti-inflammatory, antiviral, and antiprotozoal activities, etc. Numerous methods are available for the formation of pyrimidine derivatives that have been reported in the literature. The advantage of pyrimidine as a starting material for different therapeutically potent derivatives has given momentum to this research. This review aims to report the new work on the synthesis of marketed drugs which consist pyrimidine moiety.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:22 |
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| Enthalten in: |
Mini-reviews in ... medicinal chemistry - 22(2022), 6, Seite 20 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kumar, Amit [VerfasserIn] |
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| Links: |
FID Access [lizenzpflichtig] |
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| Umfang: |
1 Online-Ressource (20 p) |
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| Förderinstitution / Projekttitel: |
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KFL011181583 |
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| 520 | |a Pyrimidine and its derivatives are a very important class of heterocyclic compounds that show interesting applications in the field of medicinal chemistry. Pyrimidine not only plays an important role as an organic reaction intermediate but also has a wide range of interesting biological activities viz. antibacterial, antifungal, anticancer, anti-inflammatory, antiviral, and antiprotozoal activities, etc. Numerous methods are available for the formation of pyrimidine derivatives that have been reported in the literature. The advantage of pyrimidine as a starting material for different therapeutically potent derivatives has given momentum to this research. This review aims to report the new work on the synthesis of marketed drugs which consist pyrimidine moiety | ||
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