Outcome After Acute Ischemic Stroke Treatment During Covid-19 Outbreakin South-East Tuscany / Maurizio Acampa, Valentina Peresso, Pietro Enea Lazzerini, Carlo Domenichelli, Francesca Guideri, Rossana Tassi, Stefano Dami, Roberto Marconi, Giovanni Linoli, Giulia Peppoloni, Simone Gallerini, Alessandra Cartocci, Sandra Bracco, Giuseppe Martini

Background: During Covid-19 pandemic, the Italian National Healthcare Service hasfaced increasing pressure, especially in Northern Italy. Even in less-affected regions, such as Tuscany,the changes in the healthcare system to prevent Covid-19 spread resulted in difficulty in treatingtime-dependent disorders like ischemic stroke rapidly. Objective: The aim of our study was to assess the outcome after acute ischemic stroke treatmentsduring the Covid-19 spread in comparison with a similar period of the previous year in Siena-Hospital(Hub center in the South-East Tuscany). Methods: We enrolled all patients admitted to Siena-Hospital for ischemic stroke and submittedthem to acute treatments (intravenous and/or mechanical thrombolysis) between February 21st andMay 18th, 2020 (study group, n:38) and compared the results with ischemic strokes acutely treatedin a similar period in 2019 (control group, n:39). The modified Rankin scale score was assessed at90 days to evaluate a 3-month clinical outcome. Results: In the study group, the time from symptoms onset to hospital arrival and the door-to-groinpuncture time were significantly more prolonged than in the control group. In moderate-severestrokes, the 3-month mortality was significantly higher in the study group (31% vs. 6%; p=0.01),and the number of patients with poor functional outcomes was significantly higher in the studygroup (73% vs. 44%; p=0.03). Conclusion: During the lockdown period due to Covid-19 pandemic, patients with acute ischemicstroke had a worse prognosis. These findings suggest the need to improve the health system organizationto guarantee an appropriate treatment during the pandemic, including the patients that arenot affected by Covid-19.

Medienart:	E-Artikel

Erscheinungsjahr:	2021
Erschienen:	2021

Enthalten in:	Zur Gesamtaufnahme - volume:21
Enthalten in:	Cardiovascular & hematological disorders, drug targets - 21(2021), 3, Seite 6

Sprache:	Englisch

Beteiligte Personen:

Acampa, Maurizio [VerfasserIn] Peresso, Valentina [VerfasserIn] Lazzerini, Pietro Enea [VerfasserIn] Domenichelli, Carlo [VerfasserIn] Guideri, Francesca [VerfasserIn] Tassi, Rossana [VerfasserIn] Dami, Stefano [VerfasserIn] Marconi, Roberto [VerfasserIn] Linoli, Giovanni [VerfasserIn] Peppoloni, Giulia [VerfasserIn] Gallerini, Simone [VerfasserIn] Cartocci, Alessandra [VerfasserIn] Bracco, Sandra [VerfasserIn] Martini, Giuseppe [VerfasserIn]

Links:	FID Access [lizenzpflichtig]

Umfang:	1 Online-Ressource (6 p)

Förderinstitution / Projekttitel:

PPN (Katalog-ID):	KFL011148241