Parvovirus B19 Seroprevalence in Women with Bad Obstetric History inKirkuk / Abdulghani Mohamed Alsamarai, Hala Majeed Hassan, Mohamed Almoustafa Alsamarai, Zainab Khalil Aljumaili

Background: In the Iraqi community, abnormal pregnancy forms a major social and psychologicalhealth problem. The underlying etiology of this health phenomenon was varied and includedsets of infections and autoimmune diseases. Globally human parvovirus 19 infection is commonand the infection attributes to bad obstetric outcomes. The global maternal parvovirus B19 remoteinfection rate was within a range of 13.2% to 97.9%, while the range of acute infection wasbetween 0.5% to 97.9%. In Arab countries, the IgG seroprevalence was from 53.3% to 74%, whileIgM seroprevalence range was 2.2% to 84%. Objective: To evaluate the role of ParvovirusB19 as an etiology of bad obstetric outcome in womenin Kirkuk, Iraq. Materials and Methods: Descriptive Case Control Study. Women included in the study were recruitedfrom Kirkuk General Hospital and their age ranged from 14 to 48 years. A total of 663 womenwere included in the study, of them 237 were not pregnant, while 215 were pregnant. Additionally,the study included 211 women with inevitable abortion. Control group (306 women) womenwith a history of normal pregnancy included (Pregnant= 149; non-pregnant= 157). Clinical and laboratoryinvestigations were conducted on all patients and control groups to exclude other causes.Medical and obstetric data and demographic characteristics were gathered through interviews accordingto a previously designed questionnaire. ELISA kits were used to determine Parvovirus B19IgM and IgG antibodies. Results: The overall parvovirus seroprevalence was 93% and with no significant difference betweenwomen with normal (89.5%) and those with abnormal (93.1%) pregnancy outcomes. In addition,parvovirus IgM overall seroprevalence was at56.3%. Furthermore, current parvovirus infectionwas higher in women with BOH (52.6%) than that in women with normal pregnancy (49.7%)outcomes. Parvovirus IgM seroprevalence was 52.6% in women with BOH and 49.7% in womenwith normal pregnancy, however, the difference was not statistically significant. In contrast, theacute infection with parvovirus was significantly (X2=11.8, P=0.001) lower in women with normalpregnancy (49.7%) than in those with inevitable abortion (64.9%). While the IgG seroprevalencedifference was not significant between the two groups, infection seroprevalence was more frequentin housewives, uneducated women, large families, non-smokers, in rural areas, non-animal exposureareas, women with repeated abortion, congenital anomalies and anaemia. Conclusion: Parvovirus B19 infection may be with bad obstetric outcomes if occurred during pregnancyand OR confirmed a significant association of the infection with parvovirus with smoking,occupation, crowding index, education, animal exposure and the number of repeated abortion.

Medienart:	E-Artikel

Erscheinungsjahr:	2021
Erschienen:	2021

Enthalten in:	Zur Gesamtaufnahme - volume:20
Enthalten in:	Anti-inflammatory & anti-allergy agents in medicinal chemistry - 20(2021), 4, Seite 8

Sprache:	Englisch

Beteiligte Personen:	Alsamarai, Abdulghani Mohamed [VerfasserIn] Hassan, Hala Majeed [VerfasserIn] Alsamarai, Mohamed Almoustafa [VerfasserIn] Aljumaili, Zainab Khalil [VerfasserIn]

Links:	FID Access [lizenzpflichtig]

Umfang:	1 Online-Ressource (8 p)

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PPN (Katalog-ID):	KFL011145218