Metabolite Profiling, Isolation of Cyclic Polyols, Antioxidant and Anti-inflammatory Activities ofAegle Marmelos: NMR and GC-MS Based Metabolomics Study / Ritu Tiwari, Tusha Tripathi, Yasir A. Khan, Annie Gupta, Mahaveer Dhobi, Sushma Srivastava, Brahmanand Singh, Karuna Shanker, Vivekanandan Kalaiselvan, Gyanendra N Singh
ABSTRACT The primary and secondary metabolites of different parts of Aegle marmelos were isolated, the cyclic polyols were characterized. The antioxidant activities in vitro and in a cell-based human liver AML-12 cells and the anti-inflammatory activities of isolated quinic acid and ethanol extract of leaves were determined. One hundred and thirty two primary and secondary metabolites were identified in the extracts by HPLC, GC-MS, and NMR. Results demonstrated A. marmelos as an antioxidant and a sustainable by-product with therapeutic potential for treating inflammation.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2021 |
---|---|
Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
---|---|
Enthalten in: |
Journal of herbs, spices & medicinal plants - 27(2021), 1, Seite 68-82 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Tiwari, Ritu [VerfasserIn] |
---|
Links: |
FID Access [lizenzpflichtig] |
---|
Themen: |
Anti-inflammatory activity |
---|
Umfang: |
1 Online-Ressource (15 p) |
---|
doi: |
10.1080/10496475.2020.1786873 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
KFL011119276 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | KFL011119276 | ||
003 | DE-627 | ||
005 | 20230713210808.0 | ||
007 | cr uuu---uuuuu | ||
008 | 230609s2021 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1080/10496475.2020.1786873 |2 doi | |
035 | |a (DE-627)KFL011119276 | ||
035 | |a (KFL)prod_LgpH_10.1080/10496475.2020.1786873 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
084 | |a PHARM |q DE-84 |2 fid | ||
100 | 1 | |a Tiwari, Ritu |e verfasserin |4 aut | |
245 | 1 | 0 | |a Metabolite Profiling, Isolation of Cyclic Polyols, Antioxidant and Anti-inflammatory Activities ofAegle Marmelos: NMR and GC-MS Based Metabolomics Study |c Ritu Tiwari, Tusha Tripathi, Yasir A. Khan, Annie Gupta, Mahaveer Dhobi, Sushma Srivastava, Brahmanand Singh, Karuna Shanker, Vivekanandan Kalaiselvan, Gyanendra N Singh |
264 | 1 | |c 2021 | |
300 | |a 1 Online-Ressource (15 p) | ||
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a ABSTRACT The primary and secondary metabolites of different parts of Aegle marmelos were isolated, the cyclic polyols were characterized. The antioxidant activities in vitro and in a cell-based human liver AML-12 cells and the anti-inflammatory activities of isolated quinic acid and ethanol extract of leaves were determined. One hundred and thirty two primary and secondary metabolites were identified in the extracts by HPLC, GC-MS, and NMR. Results demonstrated A. marmelos as an antioxidant and a sustainable by-product with therapeutic potential for treating inflammation | ||
653 | |a Antioxidant activity | ||
653 | |a anti-inflammatory activity | ||
653 | |a cyclic polyols | ||
653 | |a NMR | ||
653 | |a GC-MS | ||
700 | 1 | |a Tripathi, Tusha |e verfasserin |4 aut | |
700 | 1 | |a Khan, Yasir A. |e verfasserin |4 aut | |
700 | 1 | |a Gupta, Annie |e verfasserin |4 aut | |
700 | 1 | |a Dhobi, Mahaveer |e verfasserin |4 aut | |
700 | 1 | |a Srivastava, Sushma |e verfasserin |4 aut | |
700 | 1 | |a Singh, Brahmanand |e verfasserin |4 aut | |
700 | 1 | |a Shanker, Karuna |e verfasserin |4 aut | |
700 | 1 | |a Kalaiselvan, Vivekanandan |e verfasserin |4 aut | |
700 | 1 | |a Singh, Gyanendra N |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of herbs, spices & medicinal plants |d Philadelphia, Pa. : Routledge, Taylor & Francis Group, 1992 |g 27(2021), 1, Seite 68-82 |h Online-Ressource |w (DE-627)KFL000088668 |w (DE-600)2091230-4 |w (DE-576)302969586 |x 1540-3580 |7 nnns |
773 | 1 | 8 | |g volume:27 |g year:2021 |g number:1 |g pages:68-82 |
856 | 4 | 0 | |u http://pharmazie.proxy.fid-lizenzen.de/fid/tandf-ejournals-pharmazie/doi.org/10.1080/10496475.2020.1786873 |m X:KFL |x Resolving-System |y FID Access |z lizenzpflichtig |
912 | |a ZDB-1-TFE | ||
912 | |a GBV_KFL | ||
912 | |a FID-PHARM | ||
935 | |i IMPORT_0628_prod_LgpH_02 | ||
951 | |a AR | ||
952 | |d 27 |j 2021 |e 1 |h 68-82 |