Metabolite Profiling, Isolation of Cyclic Polyols, Antioxidant and Anti-inflammatory Activities ofAegle Marmelos: NMR and GC-MS Based Metabolomics Study / Ritu Tiwari, Tusha Tripathi, Yasir A. Khan, Annie Gupta, Mahaveer Dhobi, Sushma Srivastava, Brahmanand Singh, Karuna Shanker, Vivekanandan Kalaiselvan, Gyanendra N Singh

ABSTRACT The primary and secondary metabolites of different parts of Aegle marmelos were isolated, the cyclic polyols were characterized. The antioxidant activities in vitro and in a cell-based human liver AML-12 cells and the anti-inflammatory activities of isolated quinic acid and ethanol extract of leaves were determined. One hundred and thirty two primary and secondary metabolites were identified in the extracts by HPLC, GC-MS, and NMR. Results demonstrated A. marmelos as an antioxidant and a sustainable by-product with therapeutic potential for treating inflammation.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

Journal of herbs, spices & medicinal plants - 27(2021), 1, Seite 68-82

Sprache:

Englisch

Beteiligte Personen:

Tiwari, Ritu [VerfasserIn]
Tripathi, Tusha [VerfasserIn]
Khan, Yasir A. [VerfasserIn]
Gupta, Annie [VerfasserIn]
Dhobi, Mahaveer [VerfasserIn]
Srivastava, Sushma [VerfasserIn]
Singh, Brahmanand [VerfasserIn]
Shanker, Karuna [VerfasserIn]
Kalaiselvan, Vivekanandan [VerfasserIn]
Singh, Gyanendra N [VerfasserIn]

Links:

FID Access [lizenzpflichtig]

Themen:

Anti-inflammatory activity
Antioxidant activity
Cyclic polyols
GC-MS
NMR

Umfang:

1 Online-Ressource (15 p)

doi:

10.1080/10496475.2020.1786873

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

KFL011119276