A Novel Desensitization Protocol for Infliximab Hypersensitivity in a 13-Year Old Patient with Pustular Psoriasis / Sapan Kumar Behera, Sandhiya Selvarajan, Jerene Mathews, Chandana Shajil, Saibal Das, Malathi Munisamy, Alphienes Stanley Xavier
Background: Drug hypersensitivity reactions to infliximab have been reported in pediatric patients. At times, these patients may need infliximab administration in spite of hypersensitivity. However, only a few reports of desensitization protocols are available in the literature in pediatric patients. Case Report: We report a case of immediate hypersensitivity reaction to intravenous infliximab in a 13-year-old child suffering from pustular psoriasis who eventually underwent a 14 step desensitization protocol for the administration of infliximab in a pediatric intensive care unit. Results and Conclusion: Although our desensitization protocol was safe and effective, we recommend the entire desensitization procedure to be performed under the supervision of experienced personnel in a pediatric intensive care unit. Future studies with larger sample size are needed to confirm our findings.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
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| Enthalten in: |
Current drug safety - 14(2019), 2, Seite 158- |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Behera, Sapan Kumar [VerfasserIn] |
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| Links: |
FID Access [lizenzpflichtig] |
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| Umfang: |
1 Online-Ressource (5 p) |
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| Förderinstitution / Projekttitel: |
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| 245 | 1 | 2 | |a A Novel Desensitization Protocol for Infliximab Hypersensitivity in a 13-Year Old Patient with Pustular Psoriasis |c Sapan Kumar Behera, Sandhiya Selvarajan, Jerene Mathews, Chandana Shajil, Saibal Das, Malathi Munisamy, Alphienes Stanley Xavier |
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| 520 | |a Background: Drug hypersensitivity reactions to infliximab have been reported in pediatric patients. At times, these patients may need infliximab administration in spite of hypersensitivity. However, only a few reports of desensitization protocols are available in the literature in pediatric patients. Case Report: We report a case of immediate hypersensitivity reaction to intravenous infliximab in a 13-year-old child suffering from pustular psoriasis who eventually underwent a 14 step desensitization protocol for the administration of infliximab in a pediatric intensive care unit. Results and Conclusion: Although our desensitization protocol was safe and effective, we recommend the entire desensitization procedure to be performed under the supervision of experienced personnel in a pediatric intensive care unit. Future studies with larger sample size are needed to confirm our findings | ||
| 700 | 1 | |a Selvarajan, Sandhiya |e verfasserin |4 aut | |
| 700 | 1 | |a Mathews, Jerene |e verfasserin |4 aut | |
| 700 | 1 | |a Shajil, Chandana |e verfasserin |4 aut | |
| 700 | 1 | |a Das, Saibal |e verfasserin |4 aut | |
| 700 | 1 | |a Munisamy, Malathi |e verfasserin |4 aut | |
| 700 | 1 | |a Xavier, Alphienes Stanley |e verfasserin |4 aut | |
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