Inactivation of oral biofilms using visible light and water-filtered infrared A radiation and indocyanine green / Thomas Burchard, Lamprini Karygianni, Elmar Hellwig, Marie Follo, Thomas Wrbas, Annette Wittmer, Kirstin Vach, Ali Al-Ahmad
Aim:To investigate the antimicrobial photodynamic therapy (aPDT) of visible light and water-filtered infrared A radiation in combination with indocyanine green (ICG) on planktonic oral microorganisms as well as on oral biofilm.Methods:The irradiation was conducted for 5 min in combination with ICG. Treatment with chlorhexidine served as a positive control. The number of colony forming units and bacterial vitality were quantified.Results:All tested bacterial strains and salivary bacteria were killed at a level of 3log10.The colony forming units of the initial mature oral biofilms were strongly reduced. The high bactericidal effect of aPDT was confirmed by live/dead staining.Conclusion:The aPDT using visible light and water-filtered infrared A radiation and ICG has the potential to treat periodontitis and peri-implantitis. Aim: Methods: Results: 10. Conclusion.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
Future medicinal chemistry - 11(2019), 14, Seite 1721- |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Burchard, Thomas [VerfasserIn] |
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| Links: |
FID Access [lizenzpflichtig] |
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| Umfang: |
1 Online-Ressource (19 p) |
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| doi: |
10.4155/fmc-2018-0522 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Aim:To investigate the antimicrobial photodynamic therapy (aPDT) of visible light and water-filtered infrared A radiation in combination with indocyanine green (ICG) on planktonic oral microorganisms as well as on oral biofilm.Methods:The irradiation was conducted for 5 min in combination with ICG. Treatment with chlorhexidine served as a positive control. The number of colony forming units and bacterial vitality were quantified.Results:All tested bacterial strains and salivary bacteria were killed at a level of 3log10.The colony forming units of the initial mature oral biofilms were strongly reduced. The high bactericidal effect of aPDT was confirmed by live/dead staining.Conclusion:The aPDT using visible light and water-filtered infrared A radiation and ICG has the potential to treat periodontitis and peri-implantitis. Aim: Methods: Results: 10. Conclusion | ||
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| 700 | 1 | |a Al-Ahmad, Ali |e verfasserin |4 aut | |
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