Enantiomeric analysis of clenbuterol in Chinese people by LC–MS/MS to distinguish doping abuse from meat contamination / Genye He, Linghui Sheng, Jianli Zhang, Yun Wu, Xuxiao Zhao, Youxuan Xu, Jianghai Lu
Aim:Follow-up investigations are often required for clenbuterol-positive cases. A method to distinguish doping abuse from meat contamination was developed.Materials & methods:A total of 26 volunteers were recruited to ingest clenbuterol contaminated-pork and clenbuterol tablets.Results:For 20 volunteers, after ingestion of contaminated-pork, R-(-)/S-(+)-clenbuterol ratio was <1.0, while the value was >1.0 after taking clenbuterol tablets. However, after taking clenbuterol tablets, some ratio points of the other six volunteers were between 0.9 and 1.0. A case of an abnormal cold and fever, which returned to normal after recovery, was also reported firstly.Conclusion:A change in R-(-)/S-(+)-clenbuterol was reported in the Chinese population initially. A ratio of 0.9 was recommended in doping related cases for the Chinese population. Aim: Materials & methods: Results: Conclusion.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Bioanalysis - 12(2020), 11, Seite 783- |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
He, Genye [VerfasserIn] |
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| Links: |
FID Access [lizenzpflichtig] |
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| Umfang: |
1 Online-Ressource (8 p) |
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| doi: |
10.4155/bio-2020-0003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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KFL001042149 |
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| 245 | 1 | 0 | |a Enantiomeric analysis of clenbuterol in Chinese people by LC–MS/MS to distinguish doping abuse from meat contamination |c Genye He, Linghui Sheng, Jianli Zhang, Yun Wu, Xuxiao Zhao, Youxuan Xu, Jianghai Lu |
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| 520 | |a Aim:Follow-up investigations are often required for clenbuterol-positive cases. A method to distinguish doping abuse from meat contamination was developed.Materials & methods:A total of 26 volunteers were recruited to ingest clenbuterol contaminated-pork and clenbuterol tablets.Results:For 20 volunteers, after ingestion of contaminated-pork, R-(-)/S-(+)-clenbuterol ratio was <1.0, while the value was >1.0 after taking clenbuterol tablets. However, after taking clenbuterol tablets, some ratio points of the other six volunteers were between 0.9 and 1.0. A case of an abnormal cold and fever, which returned to normal after recovery, was also reported firstly.Conclusion:A change in R-(-)/S-(+)-clenbuterol was reported in the Chinese population initially. A ratio of 0.9 was recommended in doping related cases for the Chinese population. Aim: Materials & methods: Results: Conclusion | ||
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| 700 | 1 | |a Zhao, Xuxiao |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Youxuan |e verfasserin |4 aut | |
| 700 | 1 | |a Lu, Jianghai |e verfasserin |4 aut | |
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