Tularemia transmission to humans : a multifaceted surveillance approach

Tularemia has sustained seroprevalence in Eurasia, withestimates as high as 15% in endemic regions. The purpose of thisreport is to characterise the current epidemiology ofFrancisella tularensis subspecies holarctica in Georgia. Three surveillance activities are summarised: (1) acute infections captured in Georgia's notifiable disease surveillance system, (2) infectious disease seroprevalence study of military volunteers, and (3) a study of seroprevalence and risk factors in endemic regions. Descriptive analyses of demographic, exposure and clinical factors were conducted for the surveillance studies; bivariate analyses were computed to identify risk factors of seropositivity using likelihood ratio χ² tests or Fisher's exact tests. Of the 19 incident cases reported between 2014 and August 2017, 10 were confirmed and nine met the presumptive definition; the estimated annual incidence was 0.12/100 000. The first cases of tularemia in Western Georgia were reported. Seroprevalences of antibodies for F. tularensis were 2.0% for military volunteers and 5.0% for residents in endemic regions. Exposures correlated with seropositivity included work with hay and contact with multiple types of animals. Seroprevalence studies conducted periodically may enhance our understanding of tularemia in countries with dramatically underestimated incidence rates..

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:146

Sprache:

Englisch

Beteiligte Personen:

Akhvlediani, N. [VerfasserIn]
Burjanadze, I. [VerfasserIn]
Baliashvili, D. [VerfasserIn]
Tushishvili, T. [VerfasserIn]
Broladze, M. [VerfasserIn]
Navdarashvili, A. [VerfasserIn]
Dolbadze, S. [VerfasserIn]
Chitadze, N. [VerfasserIn]
Topuridze, M. [VerfasserIn]
Imnadze, P. [VerfasserIn]
Kazakhashvili, N. [VerfasserIn]
Tsertsvadze, T. [VerfasserIn]
Kuchuloria, T. [VerfasserIn]
Akhvlediani, T. [VerfasserIn]
McNutt, L.-A. [VerfasserIn]
Chanturia, G. [VerfasserIn]

Links:

Volltext

Themen:

Epidemiology
Georgia
Research-article
Surveillance
Tularemia

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

JST136754171