RATIONAL TESTING: Interpreting and investigating proteinuria

LEARNING POINTS Proteinuria may indicate important glomerular or tubular pathology related to side effects from drugs such as NSAIDs In patients with persistently positive dipstick tests, protanuria is best quantified by measuring albumin: creatinine ratio or protein:creatinine ratio Refer the patient if albumin:creatinine ratio > 70 mg/mmol (or > 30 mg/mmol if concomitant haematuria); protein:creatinine ratio > 100 mg/mmol (or > 50 mg/mmol if concomitant haematuria), or other renal pathology is present Urgent referral for heavy proteinuria (protein:creatinine ratio > 300 mg/mmol) and a low serum albumin (< 30 g/L) Proteinuria and impaired renal function (low estimated glomerular filtration rate) independently and additively correlate with risk of progression of renal disease and with cardiovascular events.

Medienart:

E-Artikel

Erscheinungsjahr:

2012

Erschienen:

2012

Enthalten in:

Zur Gesamtaufnahme - volume:344

Sprache:

Englisch

Beteiligte Personen:

Browne, Oliver T [VerfasserIn]
Bhandari, Sunil [VerfasserIn]

Links:

Volltext

Themen:

Biological sciences
Health sciences
Physical sciences
Research-article

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

JST097807958