No Teratogenic Effect after Clotrimazole Therapy during Pregnancy
We evaluated the potential teratogenic effects of vaginal and/or topical administration of clotrimazole in the large population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities (1980-1992). The dataset included 18,515 case pregnancies and 32,804 control pregnancies; 7.1% of case and 7.7% of control women used clotrimazole during pregnancy. Clotrimazole use was not clearly associated with an increase in the total (fetal + birth) prevalence of any congenital abnormality group. There was, however, a suggestion that clotrimazole use was associated with a decrease in the prevalence of undescended testis (prevalence odds ratio = 0.72; 95% confidence interval = 0.54-0.95)..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
1999 |
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| Erschienen: |
1999 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Epidemiology - 10(1999), 4, Seite 437-440 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Czeizel, Andrew E. [VerfasserIn] |
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| Links: |
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| BKL: | |
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| Themen: |
Case-control study |
| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
JST031408974 |
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| 245 | 1 | 0 | |a No Teratogenic Effect after Clotrimazole Therapy during Pregnancy |
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| 520 | |a We evaluated the potential teratogenic effects of vaginal and/or topical administration of clotrimazole in the large population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities (1980-1992). The dataset included 18,515 case pregnancies and 32,804 control pregnancies; 7.1% of case and 7.7% of control women used clotrimazole during pregnancy. Clotrimazole use was not clearly associated with an increase in the total (fetal + birth) prevalence of any congenital abnormality group. There was, however, a suggestion that clotrimazole use was associated with a decrease in the prevalence of undescended testis (prevalence odds ratio = 0.72; 95% confidence interval = 0.54-0.95). | ||
| 540 | |a Copyright 1999 Epidemiology Resources Inc. | ||
| 650 | 4 | |a Clotrimazole | |
| 650 | 4 | |a Vulvovaginal candidosis | |
| 650 | 4 | |a Teratogenic effect | |
| 650 | 4 | |a Congenital abnormalities | |
| 650 | 4 | |a Case-control study | |
| 655 | 4 | |a research-article | |
| 700 | 1 | |a Tóth, Márta |e verfasserin |4 aut | |
| 700 | 1 | |a Rockenbauer, Magda |e verfasserin |4 aut | |
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| 856 | 4 | 0 | |u https://www.jstor.org/stable/3703565 |3 Volltext |
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