METHOD OF IMMMUNOFOCUSING AN IMMUNE RESPONSE
The present disclosure relates to vaccines, therapeutic antibodies and methods of making such vaccines and antibodies. More specifically, the disclosure relates to methods of immunofocusing an immune response to a protein having both neutralizing epitopes and non-neutralizing epitopes, such that the immune response is preferentially, or completely, directed towards, or away from, a particular portion of the antigen. The disclosure also relates to methods of using the disclosed vaccines and immunofocused proteins to vaccinate an individual and to detect neutralizing antibodies in a sample from an individual..
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Patent| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Europäisches Patentamt - (2024) vom: 01. Feb. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
TOLIA NIRAJ HARISH [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2024-02-01, Last update posted on www.tib.eu: 2024-02-23, Last updated: 2024-03-01 |
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| Patentnummer: |
WO2024026301 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA019213751 |
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| 520 | |a The present disclosure relates to vaccines, therapeutic antibodies and methods of making such vaccines and antibodies. More specifically, the disclosure relates to methods of immunofocusing an immune response to a protein having both neutralizing epitopes and non-neutralizing epitopes, such that the immune response is preferentially, or completely, directed towards, or away from, a particular portion of the antigen. The disclosure also relates to methods of using the disclosed vaccines and immunofocused proteins to vaccinate an individual and to detect neutralizing antibodies in a sample from an individual. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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