METHODS OF TREATING CANCER WITH KINASE INHIBITORS
Aspects of the present disclosure are directed to methods for treating a subject having cancer. Certain aspects relate to treating a subject for lung cancer by administering a kinase inhibitor to a subject determined, from analysis of tumor DNA from the subject, to have an EGFR mutation of a particular classification. Further aspects relate to methods for treating a subject for lung cancer by detecting an EGFR mutation of a particular classification in tumor DNA from the subject and administering an effective amount of a kinase inhibitor to the subject. Also disclosed are methods for stratifying and prognosing subjects based on EGFR mutation classification..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 06. Dez. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ROBICHAUX JACQULYNE P [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-12-06, Last update posted on www.tib.eu: 2024-03-05, Last updated: 2024-03-08 |
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| Patentnummer: |
EP4284950 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018723306 |
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| 520 | |a Aspects of the present disclosure are directed to methods for treating a subject having cancer. Certain aspects relate to treating a subject for lung cancer by administering a kinase inhibitor to a subject determined, from analysis of tumor DNA from the subject, to have an EGFR mutation of a particular classification. Further aspects relate to methods for treating a subject for lung cancer by detecting an EGFR mutation of a particular classification in tumor DNA from the subject and administering an effective amount of a kinase inhibitor to the subject. Also disclosed are methods for stratifying and prognosing subjects based on EGFR mutation classification. | ||
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| 650 | 4 | |a tec | |
| 650 | 4 | |a G01N: Investigating or analysing materials by determining their chemical or physical properties (measuring or testing processes other than immunoassay, involving enzymes or microorganisms c12m, c12q) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
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