Drug-loaded Prussian blue nanoparticles as well as preparation method and application thereof
The invention relates to the technical field of medicines, in particular to a drug-loaded Prussian blue nanoparticle as well as a preparation method and application thereof, and aims to improve the drug loading capacity of a drug carrier. The drug-loaded Prussian blue nanoparticle comprises a platelet membrane and a Prussian blue carrier, the platelet membrane coats the surface of the outer layer of Prussian blue, the Prussian blue carrier is of a hollow mesoporous structure, and the Prussian blue carrier is internally loaded with arteplase. The hollow structure of the Prussian blue nanoparticle is large, more drug loading space is provided, the drug loading capacity of Prussian blue can be greatly improved, meanwhile, the use amount of Prussian blue can be reduced, and the production cost is saved..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 12. Sept. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHANG WENLI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-09-12, Last update posted on www.tib.eu: 2023-12-12, Last updated: 2023-12-15 |
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| Patentnummer: |
CN116725982 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018718035 |
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| 520 | |a The invention relates to the technical field of medicines, in particular to a drug-loaded Prussian blue nanoparticle as well as a preparation method and application thereof, and aims to improve the drug loading capacity of a drug carrier. The drug-loaded Prussian blue nanoparticle comprises a platelet membrane and a Prussian blue carrier, the platelet membrane coats the surface of the outer layer of Prussian blue, the Prussian blue carrier is of a hollow mesoporous structure, and the Prussian blue carrier is internally loaded with arteplase. The hollow structure of the Prussian blue nanoparticle is large, more drug loading space is provided, the drug loading capacity of Prussian blue can be greatly improved, meanwhile, the use amount of Prussian blue can be reduced, and the production cost is saved. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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