SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES
The present disclosure relates to compounds, and to their pharmaceutical compositions, that inhibit dipeptidyl peptidase IV (DPP4). Hie compounds selectively promote the proliferation of alveolar type 2 cells (AEC2s) and are useful in therapeutic methods of treating diseases whose etiology, for example, derives from epithelial degeneration and maladaptive remodeling, such as pulmonary' diseases like idiopathic pulmonary fibrosis (IFF), acute respiratory' distress syndrome (ARDS), and infant respiratory' distress syndromes (IRDS)..
Medienart: |
Patent |
---|
Erscheinungsjahr: |
2023 |
---|---|
Erschienen: |
2023 |
Enthalten in: |
Europäisches Patentamt - (2023) vom: 22. Nov. Zur Gesamtaufnahme - year:2023 |
---|
Sprache: |
Englisch |
---|
Beteiligte Personen: |
BOLLONG MICHAEL [VerfasserIn] |
---|
Links: |
Volltext [kostenfrei] |
---|
Themen: |
Sonstige Themen: |
---|
Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-11-22, Last update posted on www.tib.eu: 2024-01-23, Last updated: 2024-01-26 |
---|
Patentnummer: |
EP4277619 |
---|
Förderinstitution / Projekttitel: |
|
---|
PPN (Katalog-ID): |
EPA018648711 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | EPA018648711 | ||
003 | DE-627 | ||
005 | 20240126103906.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231201s2023 xx |||||o 00| ||eng c | ||
035 | |a (DE-627)EPA018648711 | ||
035 | |a (EPA)EP4277619 | ||
035 | |a (EPA)80222163 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 0 | |a BOLLONG MICHAEL |e verfasserin |4 aut | |
245 | 1 | 0 | |a SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES |
264 | 1 | |c 2023 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Source: www.epo.org (no modifications made), First posted: 2023-11-22, Last update posted on www.tib.eu: 2024-01-23, Last updated: 2024-01-26 | ||
520 | |a The present disclosure relates to compounds, and to their pharmaceutical compositions, that inhibit dipeptidyl peptidase IV (DPP4). Hie compounds selectively promote the proliferation of alveolar type 2 cells (AEC2s) and are useful in therapeutic methods of treating diseases whose etiology, for example, derives from epithelial degeneration and maladaptive remodeling, such as pulmonary' diseases like idiopathic pulmonary fibrosis (IFF), acute respiratory' distress syndrome (ARDS), and infant respiratory' distress syndromes (IRDS). | ||
650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
650 | 4 | |a che | |
650 | 4 | |a 615 | |
700 | 0 | |a SCHULTZ PETER |4 aut | |
700 | 0 | |a SHAO SIDA |4 aut | |
700 | 0 | |a CHATTERJEE ARNAB |4 aut | |
700 | 0 | |a CHEN JIAN |4 aut | |
700 | 0 | |a ZHANG NAN |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Europäisches Patentamt |g (2023) vom: 22. Nov. |
773 | 1 | 8 | |g year:2023 |g day:22 |g month:11 |
856 | 4 | 0 | |u https://worldwide.espacenet.com/patent/search/family/80222163/publication/EP4277619A1?q=EP4277619 |z kostenfrei |3 Volltext |
912 | |a GBV_EPA | ||
936 | u | w | |j 2023 |b 22 |c 11 |
951 | |a AR | ||
952 | |j 2023 |b 22 |c 11 |