Stable preparation of human papilloma virus virus-like particle vaccine
The invention provides a stable preparation of a human papilloma virus virus-like particle vaccine, which consists of human papilloma virus virus-like particles, a buffer solution, an osmotic pressure regulator, a surfactant and an aluminum adjuvant, and the vaccine component is the HPV virus-like particles assembled by L1 proteins of HPV6 type, 11 type, 16 type, 18 type, 31 type, 33 type, 45 type, 52 type and 58 type. And one or more HPV virus-like particles assembled by L1 proteins of other pathogenic HPV types. The preparation can enhance the stability of the vaccine and prolong the validity period of the vaccine in a water-containing preparation..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 17. Nov. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
LIU YAN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-11-17, Last update posted on www.tib.eu: 2024-01-29, Last updated: 2024-02-02 |
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| Patentnummer: |
CN117083078 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018620884 |
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| 520 | |a The invention provides a stable preparation of a human papilloma virus virus-like particle vaccine, which consists of human papilloma virus virus-like particles, a buffer solution, an osmotic pressure regulator, a surfactant and an aluminum adjuvant, and the vaccine component is the HPV virus-like particles assembled by L1 proteins of HPV6 type, 11 type, 16 type, 18 type, 31 type, 33 type, 45 type, 52 type and 58 type. And one or more HPV virus-like particles assembled by L1 proteins of other pathogenic HPV types. The preparation can enhance the stability of the vaccine and prolong the validity period of the vaccine in a water-containing preparation. | ||
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