IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS

The present invention relates to compounds inhibiting the transforming growth factor β (TGF β) type I receptor (ALK5) (hereinafter ALK5 inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of many diseases, disorders, or conditions associated with ALK5 signaling pathway..

Medienart:

Patent

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Europäisches Patentamt - (2023) vom: 02. Nov. Zur Gesamtaufnahme - year:2023

Sprache:

Englisch

Beteiligte Personen:

PIZZIRANI DANIELA [VerfasserIn]
RONCHI PAOLO [VerfasserIn]
BIAGETTI MATTEO [VerfasserIn]
GUARIENTO SARA [VerfasserIn]
PALA DANIELE [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

Sonstige Themen:
615
A61K: Preparations for medical, dental, or toilet purpose (...)
A61P: Specific therapeutic activity of chemical compounds (...)
C07D: Heterocyclic compounds (macromolecular compounds c0 (...)
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Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2023-11-02, Last update posted on www.tib.eu: 2023-11-23, Last updated: 2023-12-01

Patentnummer:

WO2023208986

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA018586252